Technology Process of 12,15-Dioxa-2,5,6,9,18-pentaazanonadecanedioic acid,
4,7,10-trioxo-3-(2-phenylethyl)-8-(phenylmethyl)-, 1-(1,1-dimethylethyl)
19-(9H-fluoren-9-ylmethyl) ester, (3R,8S)-
There total 1 articles about 12,15-Dioxa-2,5,6,9,18-pentaazanonadecanedioic acid,
4,7,10-trioxo-3-(2-phenylethyl)-8-(phenylmethyl)-, 1-(1,1-dimethylethyl)
19-(9H-fluoren-9-ylmethyl) ester, (3R,8S)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C39H42N4O6;
With
diethylamine;
In
acetonitrile;
at 20 ℃;
for 0.5h;
8-(9-fluorenylmethyloxycarbonyl-amino)-3,6-dioxaoctanoic acid;
With
HBTU; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 20h;
- Guidance literature:
-
C45H53N5O9;
With
diethylamine;
In
acetonitrile;
at 20 ℃;
for 0.5h;
3,9-Bis(tert-butoxycarbonylmethyl)-6-carboxymethyl-3,6,9-triazaundecanedioic acid-di-tert-butyl ester;
With
HBTU; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 18h;