3-Pyridinecarboxylic acid, 6-[3-[(1S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-methylethoxy]-5-[[(1- methyl-1H-pyrazol-3-yl)amino]carbonyl]phenoxy]-, methyl ester

Base Information

Chemical Name:3-Pyridinecarboxylic acid, 6-[3-[(1S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-methylethoxy]-5-[[(1- methyl-1H-pyrazol-3-yl)amino]carbonyl]phenoxy]-, methyl ester
CAS No.:919784-29-5
Molecular Formula:C27H36N4O6Si
Molecular Weight:540.692
Hs Code.:

3-Pyridinecarboxylic acid,
6-[3-[(1S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-methylethoxy]-5-[[(1-
methyl-1H-pyrazol-3-yl)amino]carbonyl]phenoxy]-, methyl ester

Synonyms:

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Chemical Property of 3-Pyridinecarboxylic acid, 6-[3-[(1S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-methylethoxy]-5-[[(1- methyl-1H-pyrazol-3-yl)amino]carbonyl]phenoxy]-, methyl ester

Chemical Property:

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Hazard Codes:

MSDS Files:: SDS file from LookChem

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Technology Process of 3-Pyridinecarboxylic acid, 6-[3-[(1S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-methylethoxy]-5-[[(1- methyl-1H-pyrazol-3-yl)amino]carbonyl]phenoxy]-, methyl ester

There total 1 articles about 3-Pyridinecarboxylic acid, 6-[3-[(1S)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-methylethoxy]-5-[[(1- methyl-1H-pyrazol-3-yl)amino]carbonyl]phenoxy]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73781-91-6
6-Chloronicotinic acid methyl ester

: 871656-61-0
3-[((1S)-2-{[(1,1,-dimethylethyl)(dimethyl)silyl]oxy}-1-methylethyl)oxy]-5-hydroxy-N-(1-methyl-1H-pyrazol-3-yl)benzamide

: 919784-29-5
methyl 6-[(3-[((1S)-2-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-1-methylethyl)oxy]-5-{[(1-methyl-1H-pyrazol-3-yl)amino]carbonyl}phenyl)oxy]pyridine-3-carboxylate

Guidance literature:: With caesium carbonate; In acetonitrile; at 160 ℃; for 1.5h; Microwave irradiation;

Reference yield:

: 919784-29-5
methyl 6-[(3-[((1S)-2-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-1-methylethyl)oxy]-5-{[(1-methyl-1H-pyrazol-3-yl)amino]carbonyl}phenyl)oxy]pyridine-3-carboxylate

: 919784-28-4
6-[(3-[((1S)-2-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-1-methylethyl)oxy]-5-{[(1-methyl-1H-pyrazol-3-yl)amino]carbonyl}phenyl)oxy]pyridine-3-carboxylic acid

Guidance literature:: methyl 6-[(3-[((1S)-2-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-1-methylethyl)oxy]-5-{[(1-methyl-1H-pyrazol-3-yl)amino]carbonyl}phenyl)oxy]pyridine-3-carboxylate; With lithium hydroxide; In tetrahydrofuran; water; at 20 ℃;

With hydrogenchloride; In water; pH=7;