4-Amino-3-chlorobenzenesulfonamide

Base Information

Chemical Name:4-Amino-3-chlorobenzenesulfonamide
CAS No.:53297-68-0
Molecular Formula:C6H7ClN2O2S
Molecular Weight:206.653
Hs Code.:2935009090
UNII:PQA6DTJ2BX
DSSTox Substance ID:DTXSID80201417
Nikkaji Number:J30.811K
Wikidata:Q83074636
Pharos Ligand ID:CWZFGV2YVQ8K
ChEMBL ID:CHEMBL7092
Mol file:53297-68-0.mol

Synonyms:2-Chloro-4-sulfamoylaniline;53297-68-0;4-Amino-3-chlorobenzenesulfonamide;Benzenesulfonamide, 4-amino-3-chloro-;4-amino-3-chlorobenzene-1-sulfonamide;4-Amino-3-chloro-benzenesulfonamide;PB 311;PQA6DTJ2BX;BRN 2099720;CHEMBL7092;MFCD01565841;PB-311;3-14-00-02189 (Beilstein Handbook Reference);3-Chlorosulfanilamide;UNII-PQA6DTJ2BX;D0YU8J;2-Chloro-4-sulphamoylaniline;3-CHLORO-SULFANILAMIDE;SCHEMBL248783;halogenosulfanilamide deriv. 5c;BDBM10863;DTXSID80201417;SULFANILAMIDE, 3-CHLORO-;AMY16442;aromatic/heteroaromatic sulfonamide 8;GS1036;AKOS000190856;SB77557;2-chloro-4-sulfamoylaniline, AldrichCPR;DS-13635;LS-31220;SY041229;4-AMINO-3-CHLOROBENZENESULPHONAMIDE;A7754;CS-0157037;FT-0768036;EN300-96476;4-AZANYL-3-CHLORANYL-BENZENESULFONAMIDE;BENZENESULPHONAMIDE, 4-AMINO-3-CHLORO-;F11675;Z316122550

Suppliers and Price of 4-Amino-3-chlorobenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-4-sulfamoylaniline
25mg
$ 45.00

Crysdot
2-Chloro-4-sulfamoylaniline 95+%
5g
$ 497.00

Crysdot
2-Chloro-4-sulfamoylaniline 95+%
10g
$ 969.00

American Custom Chemicals Corporation
2-CHLORO-4-SULFAMOYLANILINE 95.00%
5G
$ 1506.05

American Custom Chemicals Corporation
2-CHLORO-4-SULFAMOYLANILINE 95.00%
2.5G
$ 1201.49

American Custom Chemicals Corporation
2-CHLORO-4-SULFAMOYLANILINE 95.00%
1G
$ 837.99

Alichem
4-Amino-3-chlorobenzenesulfonamide
1g
$ 1564.50

Alichem
4-Amino-3-chlorobenzenesulfonamide
500mg
$ 831.30

Alichem
4-Amino-3-chlorobenzenesulfonamide
250mg
$ 480.00

AK Scientific
4-Amino-3-chlorobenzenesulfonamide
1g
$ 261.00

Total 31 raw suppliers

Chemical Property of 4-Amino-3-chlorobenzenesulfonamide

Chemical Property:

Vapor Pressure:4.46E-07mmHg at 25°C
Melting Point:161 °C
Refractive Index:1.637
Boiling Point:414.4 °C at 760 mmHg
PKA:9.83±0.60(Predicted)
Flash Point:204.4 °C
PSA：94.56000
Density:1.558 g/cm³
LogP:2.93190
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:205.9916763
Heavy Atom Count:12
Complexity:249

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-4-sulfamoylaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1S(=O)(=O)N)Cl)N

Technology Process of 4-Amino-3-chlorobenzenesulfonamide

There total 6 articles about 4-Amino-3-chlorobenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 63-74-1
sulfanilamide

: 53297-68-0
4-amino-3-chlorobenzenesulfonamide

Guidance literature:: With N-chloro-succinimide; In tetrahydrofuran; at 40 ℃; for 25h; Solvent; Temperature;

Reference yield:

: 68252-72-2
4-acetamido-3-chlorobenzenesulfonamide

: 53297-68-0
4-amino-3-chlorobenzenesulfonamide

Guidance literature:: With hydrogenchloride; for 0.75h; Heating;
DOI:10.1021/jm021123s

Reference yield:

: 16761-18-5
4-acetamido-3-chlorobenzenesulphonyl chloride

: 53297-68-0
4-amino-3-chlorobenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: NH₃ / tetrahydrofuran

2: aq. HCl / ethanol

With hydrogenchloride; ammonia; In tetrahydrofuran; ethanol;
DOI:10.1016/j.bmcl.2006.06.048