(2r,5s)-1,4-Dioxane-2,5-dicarboxylic acid

Base Information

Chemical Name:(2r,5s)-1,4-Dioxane-2,5-dicarboxylic acid
CAS No.:6938-88-1
Molecular Formula:C₆H₈O₆
Molecular Weight:176.126
Hs Code.:
NSC Number:53695
DSSTox Substance ID:DTXSID90287964
Wikidata:Q82024193

Synonyms:(2r,5s)-1,4-dioxane-2,5-dicarboxylic acid;6938-88-1;NSC53695;SCHEMBL8071886;DTXSID90287964;NSC-53695;(2R,4-dioxane-2,5-dicarboxylic acid;EN300-7439026

Suppliers and Price of (2r,5s)-1,4-Dioxane-2,5-dicarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (2r,5s)-1,4-Dioxane-2,5-dicarboxylic acid

Chemical Property:

Vapor Pressure:1.15E-09mmHg at 25°C
Boiling Point:458.1°Cat760mmHg
Flash Point:198.8°C
Density:1.558g/cm³
XLogP3:-1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:176.03208797
Heavy Atom Count:12
Complexity:178

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(OCC(O1)C(=O)O)C(=O)O
Isomeric SMILES:C1[C@@H](OC[C@H](O1)C(=O)O)C(=O)O

Technology Process of (2r,5s)-1,4-Dioxane-2,5-dicarboxylic acid

There total 13 articles about (2r,5s)-1,4-Dioxane-2,5-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

: 76245-14-2,76245-15-3
trans-5-aminomethyl-1,4-dioxane-2-carboxylic acid

: 6938-88-1
trans-1,4-dioxane-2,5-dicarboxylic acid

Guidance literature:: With water; nitric acid; for 0.666667h; Heating;
DOI:10.1248/cpb.28.2329

Reference yield:

: 87133-52-6,452055-83-3
trans-2,5-bis-(hydroxymethyl)-1,4-dioxane

: 6938-88-1
trans-1,4-dioxane-2,5-dicarboxylic acid

Guidance literature:: With potassium dichromate; sulfuric acid;
DOI:10.1021/ja01653a046

Reference yield:

: 76245-12-0
trans-1,4-dioxane-2,5-dicarbonitrile

: 6938-88-1
trans-1,4-dioxane-2,5-dicarboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: H₂, 0.3 percent NH₃ / Raney Ni / ethanol / 22 h / Ambient temperature

2: 16 percent HCl / 48 h / Ambient temperature

3: 0.7 N NaOH / Ambient temperature

4: 13 percent / c. HNO₃, H₂O / 0.67 h / Heating

With hydrogenchloride; ammonium hydroxide; sodium hydroxide; water; hydrogen; nitric acid; nickel; In ethanol;
DOI:10.1248/cpb.28.2329