Kuraridine

Base Information

• Chemical Name: Kuraridine
• CAS No.: 34981-25-4
• Molecular Formula: C26H30O6
• Molecular Weight: 438.521
• Mol file: 34981-25-4.mol

Synonyms:(E)-1-[2,4-Dihydroxy-3-(2-isopropenyl-5-methyl-hex-4-enyl)-6-methoxy-phenyl]-3-(2,4-dihydroxy-phenyl)-propenone;6'-methoxy-2,4,2',4'-tetrahydroxy-3'-lavandulylchalcone;kuraridine;kuraridin;

Chemical Property of Kuraridine

Chemical Property:

• PSA: 107.22000
• LogP: 5.50480

Purity/Quality:

Analysis control,HPLC≥95% ^*data from raw suppliers

Kuraridine ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Kuraridine

There total 17 articles about Kuraridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

(E)-3-(2,4-bis(methoxymethoxy)phenyl)-1-(6-methoxy-2,4-bis(methoxymethoxy)-3-(5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl)phenyl)prop-2-en-1-one → Kuraridine (34981-25-4)

Guidance literature:

With hydrogenchloride; In water; acetone; at 20 ℃; for 192h;

Reference yield:

2,4-Dihydroxybenzaldehyde (95-01-2) → Kuraridine (34981-25-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.5 h / 20 °C

1.2: 15 h / 20 °C

2.1: potassium hydroxide / water; methanol / 15 h / 90 °C

3.1: hydrogenchloride / acetone; water / 192 h / 20 °C

With hydrogenchloride; N-ethyl-N,N-diisopropylamine; potassium hydroxide; In methanol; water; N,N-dimethyl-formamide; acetone;

Reference yield:

5-methoxy-1,3-bis(methoxymethoxy)-2-(5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl)benzene → Kuraridine (34981-25-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: tert.-butyl lithium / tetrahydrofuran; pentane / 1 h / -78 - 20 °C / Inert atmosphere

1.2: 2 h / -78 - 20 °C / Inert atmosphere

2.1: Dess-Martin periodane / dichloromethane / 1 h / 20 °C

3.1: potassium hydroxide / water; methanol / 15 h / 90 °C

4.1: hydrogenchloride / acetone; water / 192 h / 20 °C

With hydrogenchloride; tert.-butyl lithium; Dess-Martin periodane; potassium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water; acetone; pentane;

upstream raw materials:

2,4-Dihydroxybenzaldehyde

2,4-bis(methoxymethoxy)benzaldehyde

acide 2,4,6-trihydroxybenzoique

methyl-2,6-dihydroxy-4-methoxybenzoate