2-Amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-YL)-propionic acid

Base Information

Chemical Name:2-Amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-YL)-propionic acid
CAS No.:140187-23-1
Molecular Formula:C₇H₈FN₃O₄
Molecular Weight:217.157
Hs Code.:
European Community (EC) Number:634-285-3
UNII:7CTR2LWV5M
DSSTox Substance ID:DTXSID1042609
Nikkaji Number:J669.185D
Wikipedia:5-Fluorowillardiine
Wikidata:Q4639591
Pharos Ligand ID:F29DBW7V93BX
Metabolomics Workbench ID:56464
ChEMBL ID:CHEMBL123132
Mol file:140187-23-1.mol

Synonyms:5-fluorowillardiine

Suppliers and Price of 2-Amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-YL)-propionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-(-)-5-Fluorowillardiine
50mg
$ 620.00

TRC
(S)-(-)-5-Fluorowillardiine
10mg
$ 145.00

Crysdot
(S)-(-)-5-Fluorowillardiine 98+%
10mg
$ 102.00

Crysdot
(S)-(-)-5-Fluorowillardiine 98+%
50mg
$ 413.00

ApexBio Technology
(S)-(-)-5-Fluorowillardiine
10mg
$ 229.00

ApexBio Technology
(S)-(-)-5-Fluorowillardiine
50mg
$ 929.00

American Custom Chemicals Corporation
(S)-(-)-5-FLUOROWILLARDIINE 95.00%
50MG
$ 1301.29

American Custom Chemicals Corporation
(S)-(-)-5-FLUOROWILLARDIINE 95.00%
10MG
$ 716.74

Total 16 raw suppliers

Chemical Property of 2-Amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-YL)-propionic acid

Chemical Property:

Appearance/Colour:off-white Solid
Melting Point:235ºC
Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：118.18000
Density:1.64 g/cm³
LogP:-1.21210
Storage Temp.:Store at RT
Solubility.:Aqueous Acid (Slightly)
XLogP3:-4.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:217.04988391
Heavy Atom Count:15
Complexity:354

Purity/Quality:

97% ^*data from raw suppliers

(S)-(-)-5-Fluorowillardiine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=O)NC(=O)N1CC(C(=O)O)N)F
Isomeric SMILES:C1=C(C(=O)NC(=O)N1C[C@@H](C(=O)O)N)F
Uses (S)-(-)-5-Fluorowillardiine is a potent and selective AMPA receptor agonist at hGluR1 and hGluR2 (1,2).

Technology Process of 2-Amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-YL)-propionic acid

There total 2 articles about 2-Amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-YL)-propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: