3Z,6Z,8E-Dodecatrien-1-ol

Base Information

• Chemical Name: 3Z,6Z,8E-Dodecatrien-1-ol
• CAS No.: 19926-64-8
• Molecular Formula: C12H20O
• Molecular Weight: 180.2866
• Metabolomics Workbench ID: 3256
• Mol file: 19926-64-8.mol

Synonyms:3Z,6Z,8E-Dodecatrien-1-ol;19926-64-8;(3Z,6Z,8E)-dodeca-3,6,8-trien-1-ol;(z,e,e)-3,6,8-dodecatrien-1-ol;3,6,8-Dodecatrien-1-ol, (3Z,6Z,8E)-;(z,z,e)-3,6,8-dodecatrien-1-ol;SCHEMBL1300871;LMFA05000166

Chemical Property of 3Z,6Z,8E-Dodecatrien-1-ol

Chemical Property:

• Vapor Pressure: 0.000373mmHg at 25°C
• Boiling Point: 283.2°Cat760mmHg
• Flash Point: 110.1°C
• PSA: 20.23000
• Density: 0.879g/cm³
• LogP: 3.22760
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 7
• Exact Mass: 180.151415257
• Heavy Atom Count: 13
• Complexity: 166

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC=CC=CCC=CCCO
• Isomeric SMILES: CCC/C=C/C=C\C/C=C\CCO

Technology Process of 3Z,6Z,8E-Dodecatrien-1-ol

There total 26 articles about 3Z,6Z,8E-Dodecatrien-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2,4-dimethyl-3-pentyl (Z,Z,E)-3,6,8-decatrienoate (95331-75-2) → (Z,Z,E)-3,6,8-dodecatrien-1-ol (19926-64-8)

Guidance literature:

In diethyl ether; at 0 ℃; for 0.5h;

DOI:10.1016/S0040-4039(01)81556-2

Reference yield:

(E)-3-hexen-1,6-diol (71655-17-9) → 3,6,8-dodecatrien-1-ol (19926-63-7,19926-64-8,32451-94-8,67340-90-3,67340-91-4,129258-62-4,130236-45-2,130236-46-3,130236-47-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 61 percent / (1R)-(-)-10-camphorsulfonic acid / CH₂Cl₂ / 2 h

2: 98 percent / pyridine / 7 °C

3: 98 percent / NaI / acetone / Ambient temperature

4: benzene / 24 h / Heating

5: 1) hexamethyldisilazane, n-BuLi / 1) THF, n-pentane, r.t., 1 h 2a) THF, -30 to -25 deg C, 30 min 2b) up to r.t., 2 h

With pyridine; n-butyllithium; 1,1,1,3,3,3-hexamethyl-disilazane; sodium iodide; (R)-10-camphorsulfonic acid; In dichloromethane; acetone; benzene;

DOI:10.1016/S0040-4020(01)88364-2

Reference yield:

(E)-3-hexen-1,6-diol (71655-17-9) → 3,6,8-dodecatrien-1-ol (19926-63-7,19926-64-8,32451-94-8,67340-90-3,67340-91-4,129258-62-4,130236-45-2,130236-46-3,130236-47-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 61 percent / (1R)-(-)-10-camphorsulfonic acid / CH₂Cl₂ / 2 h

2: 98 percent / pyridine / 7 °C

3: 98 percent / NaI / acetone / Ambient temperature

4: benzene / 24 h / Heating

5: 1) hexamethyldisilazane, n-BuLi / 1) THF, n-pentane, r.t., 1 h 2a) THF, -30 to -25 deg C, 30 min 2b) up to r.t., 2 h

With pyridine; n-butyllithium; 1,1,1,3,3,3-hexamethyl-disilazane; sodium iodide; (R)-10-camphorsulfonic acid; In dichloromethane; acetone; benzene;

DOI:10.1016/S0040-4020(01)88364-2

upstream raw materials:

3,6,8-dodecatrien-1-ol THP ether

2,4-dimethyl-3-pentyl (Z,Z,E)-3,6,8-decatrienoate

2-dodeca-3,6,8-trienyloxy-tetrahydro-pyran

(E)-oct-4-en-2-yn-1-ol toslyate