methyl 10-hydroxy-2,4a,6,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,11,12b,13,14,14a,14b-dodecahydropicene-2-carboxylate

Base Information

• Chemical Name: methyl 10-hydroxy-2,4a,6,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,11,12b,13,14,14a,14b-dodecahydropicene-2-carboxylate
• CAS No.: 114020-41-6
• Molecular Formula: C₃₀H₃₈O₄
• Molecular Weight: 462.629
• Mol file: 114020-41-6.mol

Synonyms:D:A-Friedo-24,26-dinoroleana-1(10),3,5,7,14-pentaen-29-oicacid, 3-hydroxy-15-methyl-2-oxo-, methyl ester, (20a)-; Netzahualcoyene

Chemical Property of methyl 10-hydroxy-2,4a,6,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,11,12b,13,14,14a,14b-dodecahydropicene-2-carboxylate

Chemical Property:

• Vapor Pressure: 1.05E-18mmHg at 25°C
• Boiling Point: 633.4°Cat760mmHg
• Flash Point: 205.9°C
• Density: 1.18g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 10-hydroxy-2,4a,6,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,11,12b,13,14,14a,14b-dodecahydropicene-2-carboxylate

There total 1 articles about methyl 10-hydroxy-2,4a,6,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,11,12b,13,14,14a,14b-dodecahydropicene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pristimerin (1258-84-0) → (2R,4aR,6bR,12bS,14aS)-6b,10,11-Trihydroxy-2,4a,6,9,12b,14a-hexamethyl-1,2,3,4,4a,5,6b,12b,13,14,14a,14b-dodecahydro-picene-2-carboxylic acid methyl ester (121688-15-1) + netzahualcoyene (114020-41-6) + C60H78O9 (121688-16-2,121786-61-6) + C60H78O9 (121688-16-2,121786-61-6)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; Ambient temperature;

DOI:10.1016/S0040-4039(01)80637-7

upstream raw materials:

pristimerin

Refernces

NEW EPIMERIC DI-TRITERPENE QUINONE ETHERS. THEIR PARTIAL SYNTHESIS AND THAT OF NETZAHUALCOYENE FROM PRISTIMERIN AND DDQ

10.1016/S0040-4039(01)80637-7

The study focuses on the isolation and partial synthesis of two new di-triterpene quinone ethers (compounds 5 and 6) from the roots of Rzedowskia tolantonguensis. Pristimerin (1) was reacted with 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) to produce a mixture of products, including netzahualcoyene (2) and alcohol 4. The structures of the synthesized compounds were determined using NMR data and compared with natural products. The study provides insights into the theorized biogenetic pathway to triterpene quinones with a rearranged netzahualcoyene skeleton.