Propanoic acid, 3-[(phenylmethyl)sulfinyl]-, 1,1-dimethylethyl ester

Base Information

• Chemical Name: Propanoic acid, 3-[(phenylmethyl)sulfinyl]-, 1,1-dimethylethyl ester
• CAS No.: 921765-53-9
• Molecular Formula: C14H20O3S
• Molecular Weight: 268.377
• Mol file: 921765-53-9.mol

Synonyms:

Chemical Property of Propanoic acid, 3-[(phenylmethyl)sulfinyl]-, 1,1-dimethylethyl ester

Chemical Property:

• PSA: 62.58000
• LogP: 3.53280

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Propanoic acid, 3-[(phenylmethyl)sulfinyl]-, 1,1-dimethylethyl ester

There total 4 articles about Propanoic acid, 3-[(phenylmethyl)sulfinyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

3-benzylsulfanylpropionic acid tert-butyl ester (921765-54-0) → 3-(phenylmethylsulfinyl)propionic acid tert-butyl ester (921765-53-9)

Guidance literature:

With aluminum oxide; oxone; water; In dichloromethane; for 3h; Heating;

DOI:10.1021/ol062315a

Reference yield:

tert-Butyl acrylate (1663-39-4,25232-27-3) → 3-(phenylmethylsulfinyl)propionic acid tert-butyl ester (921765-53-9)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / CH₂Cl₂ / 20 h / 20 °C

2: 81 percent / Oxone(R); alumina oxide; water / CH₂Cl₂ / 3 h / Heating

With aluminum oxide; oxone; water; potassium carbonate; In dichloromethane;

DOI:10.1021/ol062315a

Reference yield:

phenylmethanethiol (100-53-8) → 3-(phenylmethylsulfinyl)propionic acid tert-butyl ester (921765-53-9)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / CH₂Cl₂ / 20 h / 20 °C

2: 81 percent / Oxone(R); alumina oxide; water / CH₂Cl₂ / 3 h / Heating

With aluminum oxide; oxone; water; potassium carbonate; In dichloromethane;

DOI:10.1021/ol062315a

upstream raw materials:

3-benzylsulfanylpropionic acid tert-butyl ester

tert-Butyl acrylate

phenylmethanethiol

Downstream raw materials:

benzyl 4-methylphenyl sulfoxide

benzyl phenyl sulfoxide

benzyl 4-methoxyphenyl sulfoxide

(R)-benzyl phenyl sulphoxide