ethyl 5-formyl-2-methyl-4-(4-nitrophenyl)-1-phenyl-1H-pyrrole-3-carboxylate

Base Information

• Chemical Name: ethyl 5-formyl-2-methyl-4-(4-nitrophenyl)-1-phenyl-1H-pyrrole-3-carboxylate
• CAS No.: 22108-62-9
• Molecular Formula: C₂₁H₁₈N₂O₅
• Molecular Weight: 378.384
• Mol file: 22108-62-9.mol

Synonyms:Pyrrole-3-carboxylicacid, 5-formyl-2-methyl-4-(p-nitrophenyl)-1-phenyl-, ethyl ester (8CI); NSC216013

Chemical Property of ethyl 5-formyl-2-methyl-4-(4-nitrophenyl)-1-phenyl-1H-pyrrole-3-carboxylate

Chemical Property:

• Vapor Pressure: 2E-13mmHg at 25°C
• Boiling Point: 579.5°Cat760mmHg
• Flash Point: 304.3°C
• Density: 1.25g/cm³

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 5-formyl-2-methyl-4-(4-nitrophenyl)-1-phenyl-1H-pyrrole-3-carboxylate

There total 1 articles about ethyl 5-formyl-2-methyl-4-(4-nitrophenyl)-1-phenyl-1H-pyrrole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ estere etilico dell'acido 1-fenil-5-formil-2-metil-4-(4-nitrofenil)pirrol-3-carbossilico (22108-62-9)

Guidance literature:

2-Methyl-4-(p-nitrophenyl)-1-phenyl-pyrrol-carbonsaeure-3-ethylester, DMF/POCl3;

Reference yield:

estere etilico dell'acido 1-fenil-5-formil-2-metil-4-(4-nitrofenil)pirrol-3-carbossilico (22108-62-9) → cloruro dell'acido-1-fenil-2-metil-3-carbetossi-4-(4-nitrofenil)pirrol-5-carbossilico

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / potassium permanganate / acetone; H₂O / 10 h / Heating

2: 70 percent / thionyl chloride / benzene / 1.5 h / Heating

With potassium permanganate; thionyl chloride; In water; acetone; benzene;

Reference yield:

estere etilico dell'acido 1-fenil-5-formil-2-metil-4-(4-nitrofenil)pirrol-3-carbossilico (22108-62-9) → estere etilico dell'acido 1-(4-nitrofenil)-2-metil-9-cheto-pirrolo<1,2-a>indolo-2-carbossilico

Guidance literature:

Multi-step reaction with 3 steps

1: 65 percent / potassium permanganate / acetone; H₂O / 10 h / Heating

2: 70 percent / thionyl chloride / benzene / 1.5 h / Heating

3: 30 percent / SnCl₄ / cyclohexane / 2 h / Heating

With potassium permanganate; thionyl chloride; tin(IV) chloride; In cyclohexane; water; acetone; benzene;

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