2-Propenamide, 3-(5-(acetyloxy)-4,5-dihydro-3-furanyl)-N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-, (E)-(+)-

Base Information

Chemical Name:2-Propenamide, 3-(5-(acetyloxy)-4,5-dihydro-3-furanyl)-N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-, (E)-(+)-
CAS No.:68748-55-0
Deprecated CAS:79303-68-7
Molecular Formula:C₁₄H₁₅NO₆
Molecular Weight:293.276
Hs Code.:
DSSTox Substance ID:DTXSID201113107
Nikkaji Number:J22.274G
Metabolomics Workbench ID:107683
Mol file:68748-55-0.mol

Synonyms:2-Propenoic acid, 3-(5-(acetyloxy)-4,5-dihydro-1H-pyrrol-3-yl)-, 2-hydroxy-5-oxo-1-cyclopenten-1-yl ester, (E)-;reductiomycin

Suppliers and Price of 2-Propenamide, 3-(5-(acetyloxy)-4,5-dihydro-3-furanyl)-N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-, (E)-(+)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Reductiomycin
1mg
$ 366.00

TRC
Reductiomycin
1mg
$ 75.00

American Custom Chemicals Corporation
REDUCTIOMYCIN 95.00%
5MG
$ 500.72

American Custom Chemicals Corporation
REDUCTIOMYCIN 95.00%
1MG
$ 315.00

Adipogen Life Sciences
Reductiomycin ≥98%(HPLC)
1 mg
$ 140.00

Total 14 raw suppliers

Chemical Property of 2-Propenamide, 3-(5-(acetyloxy)-4,5-dihydro-3-furanyl)-N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-, (E)-(+)-

Chemical Property:

Vapor Pressure:4.07E-13mmHg at 25°C
Refractive Index:1.587
Boiling Point:522.8°Cat760mmHg
Flash Point:270°C
PSA：105.42000
Density:1.39g/cm³
LogP:1.82500
XLogP3:-0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:293.08993720
Heavy Atom Count:21
Complexity:572

Purity/Quality:

99% ^*data from raw suppliers

Reductiomycin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OC1CC(=CO1)C=CC(=O)NC2=C(CCC2=O)O
Isomeric SMILES:CC(=O)OC1CC(=CO1)/C=C/C(=O)NC2=C(CCC2=O)O
Uses Reductiomycin is an antibiotic with antimicrobial effects.

Technology Process of 2-Propenamide, 3-(5-(acetyloxy)-4,5-dihydro-3-furanyl)-N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-, (E)-(+)-

There total 8 articles about 2-Propenamide, 3-(5-(acetyloxy)-4,5-dihydro-3-furanyl)-N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-, (E)-(+)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4412-91-3
furan-3-methanol

: 68748-55-0,83377-76-8
2-3'-2''-acetoxy-2'',3'',-dihydrofur-4''-ylacrylamido-3-hydroxy-2-cyclopenten-1-one

Guidance literature:: Multi-step reaction with 8 steps

1: 90 percent / acetic acid / 14 h / Ambient temperature

2: 62 percent / H₂ / 5percent Rh-Al₂O₃ / ethyl acetate / 14 h / Ambient temperature

3: CrO₃*2py / CH₂Cl₂ / 0.17 h / Ambient temperature

4: benzene / 14 h / Heating

5: 57 percent / powdered zinc / acetic acid; H₂O / 4 h / Ambient temperature

6: oxalyl chloride / 0.08 h / 40 °C

7: pyridine / tetrahydrofuran / 0.33 h / -30 - 0 °C

8: 1.) powdered zinc, 2.) powdered zinc, conc. HCl / 1.) -30 deg C to room temp, 1.5 h; room temp., 1.5 h, 2.) acetic acid, room temp., 3 h

With pyridine; hydrogenchloride; oxalyl dichloride; hydrogen; dipyridine chromium trioxide; zinc; rhodium on alumina; In tetrahydrofuran; dichloromethane; water; acetic acid; ethyl acetate; benzene;
DOI:10.1039/c39820000628

Reference yield:

: Acetic acid 5-acetoxy-3-hydroxymethyl-2,5-dihydro-furan-2-yl ester

: 68748-55-0,83377-76-8
2-3'-2''-acetoxy-2'',3'',-dihydrofur-4''-ylacrylamido-3-hydroxy-2-cyclopenten-1-one

Guidance literature:: Multi-step reaction with 7 steps

1: 62 percent / H₂ / 5percent Rh-Al₂O₃ / ethyl acetate / 14 h / Ambient temperature

2: CrO₃*2py / CH₂Cl₂ / 0.17 h / Ambient temperature

3: benzene / 14 h / Heating

4: 57 percent / powdered zinc / acetic acid; H₂O / 4 h / Ambient temperature

5: oxalyl chloride / 0.08 h / 40 °C

6: pyridine / tetrahydrofuran / 0.33 h / -30 - 0 °C

7: 1.) powdered zinc, 2.) powdered zinc, conc. HCl / 1.) -30 deg C to room temp, 1.5 h; room temp., 1.5 h, 2.) acetic acid, room temp., 3 h

With pyridine; hydrogenchloride; oxalyl dichloride; hydrogen; dipyridine chromium trioxide; zinc; rhodium on alumina; In tetrahydrofuran; dichloromethane; water; acetic acid; ethyl acetate; benzene;
DOI:10.1039/c39820000628

Reference yield:

: 83343-90-2
Acetic acid 4-formyl-2,3-dihydro-furan-2-yl ester

: 68748-55-0,83377-76-8
2-3'-2''-acetoxy-2'',3'',-dihydrofur-4''-ylacrylamido-3-hydroxy-2-cyclopenten-1-one

Guidance literature:: Multi-step reaction with 5 steps

1: benzene / 14 h / Heating

2: 57 percent / powdered zinc / acetic acid; H₂O / 4 h / Ambient temperature

3: oxalyl chloride / 0.08 h / 40 °C

4: pyridine / tetrahydrofuran / 0.33 h / -30 - 0 °C

5: 1.) powdered zinc, 2.) powdered zinc, conc. HCl / 1.) -30 deg C to room temp, 1.5 h; room temp., 1.5 h, 2.) acetic acid, room temp., 3 h

With pyridine; hydrogenchloride; oxalyl dichloride; zinc; In tetrahydrofuran; water; acetic acid; benzene;
DOI:10.1039/c39820000628