PHENOL, 2-METHOXY-5-[2-(3,4,5-TRIMETHOXYPHENYL)ETHYL]-, 1-(HYDROGEN SULFATE), SODIUM SALT

Base Information

• Chemical Name: PHENOL, 2-METHOXY-5-[2-(3,4,5-TRIMETHOXYPHENYL)ETHYL]-, 1-(HYDROGEN SULFATE), SODIUM SALT
• CAS No.: 922527-87-5
• Molecular Formula: C18H22O8S.Na
• Molecular Weight: 420.416
• Hs Code.: 2920909090
• Mol file: 922527-87-5.mol

Synonyms:PHENOL, 2-METHOXY-5-[2-(3,4,5-TRIMETHOXYPHENYL)ETHYL]-, 1-(HYDROGEN SULFATE), SODIUM SALT;

Chemical Property of PHENOL, 2-METHOXY-5-[2-(3,4,5-TRIMETHOXYPHENYL)ETHYL]-, 1-(HYDROGEN SULFATE), SODIUM SALT

Chemical Property:

• PSA: 108.90000
• LogP: 3.88110

Purity/Quality:

2-METHOXY-5-[2-(3,4,5-TRIMETHOXYPHENYL)ETHYL]PHENOL-1-(HYDROGEN SULFATE)SODIUM SALT 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PHENOL, 2-METHOXY-5-[2-(3,4,5-TRIMETHOXYPHENYL)ETHYL]-, 1-(HYDROGEN SULFATE), SODIUM SALT

There total 11 articles about PHENOL, 2-METHOXY-5-[2-(3,4,5-TRIMETHOXYPHENYL)ETHYL]-, 1-(HYDROGEN SULFATE), SODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

erianin (95041-90-0) → 3,4,5,4'-tetramethoxyl-α,β-diphenylethane-3'-O-sodium sulphate (922527-87-5)

Guidance literature:

erianin; With chlorosulfonic acid; N,N-dimethyl-aniline; In dichloromethane; at -10 - -5 ℃; for 1h;

With sodium hydroxide; In dichloromethane; water; at 20 ℃; for 24h; pH=10;

Reference yield:

sodium hydroxide (1310-73-2) + erianin (95041-90-0) → 3,4,5,4'-tetramethoxyl-α,β-diphenylethane-3'-O-sodium sulphate (922527-87-5)

Guidance literature:

erianin; With chlorosulfonic acid; N,N-dimethyl-aniline; In dichloromethane; at -5 - 20 ℃; for 25h;

sodium hydroxide; In dichloromethane; water; pH=10;

Reference yield:

(3,4,5-trimethoxyphenyl)methanol (3840-31-1) → 3,4,5,4'-tetramethoxyl-α,β-diphenylethane-3'-O-sodium sulphate (922527-87-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: phosphorus tribromide / dichloromethane / 0.83 h / 20 °C

2.1: toluene / 1 h / Heating / reflux

3.1: potassium tert-butylate / tetrahydrofuran / 0.42 h / 20 °C

4.1: hydrogen / 5%-palladium/activated carbon / ethanol; ethyl acetate / 1 h / 20 °C

5.1: chlorosulfonic acid; N,N-dimethyl-aniline / dichloromethane / 1 h / -10 - -5 °C

5.2: 24 h / 20 °C / pH 10

With chlorosulfonic acid; potassium tert-butylate; hydrogen; phosphorus tribromide; N,N-dimethyl-aniline; 5%-palladium/activated carbon; In tetrahydrofuran; ethanol; dichloromethane; ethyl acetate; toluene;

upstream raw materials:

sodium hydroxide

erianin

isovanillin

(3,4,5-trimethoxyphenyl)methanol

Refernces

• 1、 -. "ERIANIN SALTS, THEIR PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME". Page/Page column 13. . Retrieved 2008/06/13.