2,6-Piperidinedimethanol, 1-(phenylmethyl)-

Base Information

Chemical Name:2,6-Piperidinedimethanol, 1-(phenylmethyl)-
CAS No.:92323-06-3
Molecular Formula:C14H21NO2
Molecular Weight:235.32200
Hs Code.:
DSSTox Substance ID:DTXSID30476936

Synonyms:2,6-Piperidinedimethanol, 1-(phenylmethyl)-;92323-06-3;SCHEMBL4247144;DTXSID30476936;ZYCSKJLOQJGMCL-UHFFFAOYSA-N;[1-benzyl-6-(hydroxymethyl)-2-piperidinyl]methanol

Suppliers and Price of 2,6-Piperidinedimethanol, 1-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2,6-Piperidinedimethanol, 1-(phenylmethyl)-

Chemical Property:

PSA：43.70000
LogP:1.33220
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:235.157228913
Heavy Atom Count:17
Complexity:204

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(N(C(C1)CO)CC2=CC=CC=C2)CO

Technology Process of 2,6-Piperidinedimethanol, 1-(phenylmethyl)-

There total 7 articles about 2,6-Piperidinedimethanol, 1-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 93025-85-5
Dimethyl N-benzyl-2,6-piperidinedicarboxylate

: 92323-06-3
1-benzyl-2,6-bis-hydroxymethyl-piperidine

Guidance literature:: Dimethyl N-benzyl-2,6-piperidinedicarboxylate; With lithium aluminium tetrahydride; In diethyl ether; for 3h; Heating / reflux;

With water;

Reference yield:

: 128581-23-7,128581-25-9
Acetic acid 6-acetoxymethyl-1-benzyl-piperidin-2-ylmethyl ester

: 92323-06-3
1-benzyl-2,6-bis-hydroxymethyl-piperidine

Guidance literature:: With potassium carbonate; In methanol;
DOI:10.1016/S0040-4039(01)93859-6

Reference yield:

: 82096-18-2
1-bromo-6-hepten-2-one

: 92323-06-3
1-benzyl-2,6-bis-hydroxymethyl-piperidine

Guidance literature:: Multi-step reaction with 5 steps

1: 85 percent / ethanol

2: 85 percent / MCPBA

3: 95 percent / 22 h / Heating

4: NaCNBH₃ / acetic acid

5: K₂CO₃ / methanol

With sodium cyanoborohydride; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In methanol; ethanol; acetic acid;
DOI:10.1016/S0040-4039(01)93859-6