1-(2-Chlorophenyl)-3-methylisoquinoline

Base Information

Chemical Name:1-(2-Chlorophenyl)-3-methylisoquinoline
CAS No.:92853-34-4
Molecular Formula:C16H12ClN
Molecular Weight:253.731
Hs Code.:
DSSTox Substance ID:DTXSID00456280
Nikkaji Number:J1.738.298E
Wikidata:Q82278630

Synonyms:1-(2-chlorophenyl)-3-methylisoquinoline;92853-34-4;Isoquinoline, 1-(2-chlorophenyl)-3-methyl-;SCHEMBL4802524;DTXSID00456280;DSSFVYZMRZPMDZ-UHFFFAOYSA-N

Suppliers and Price of 1-(2-Chlorophenyl)-3-methylisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-(2-Chlorophenyl)-3-methylisoquinoline

Chemical Property:

Melting Point:43-75 °C
Boiling Point:357.7±32.0 °C(Predicted)
PSA：12.89000
Density:1.206±0.06 g/cm3(Predicted)
LogP:4.86360
XLogP3:4.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:253.0658271
Heavy Atom Count:18
Complexity:280

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=CC=CC=C2C(=N1)C3=CC=CC=C3Cl

Technology Process of 1-(2-Chlorophenyl)-3-methylisoquinoline

There total 9 articles about 1-(2-Chlorophenyl)-3-methylisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 419535-34-5
2-chloro-N-(2-hydroxy-1-methyl-2-phenylethyl)benzamide

: 92853-34-4
1-(2-chlorophenyl)-3-methylisoquinoline

Guidance literature:: With phosphorus pentoxide; In 1,2-dichloro-benzene; Heating;
DOI:10.1021/ol017155b

Reference yield: 65.0%

: 92874-45-8
1-(2-chlorophenyl)-3-methyl-3,4-dihydroisoquinoline

: 92853-34-4
1-(2-chlorophenyl)-3-methylisoquinoline

Guidance literature:: With sulfur; In decalin; for 8h; Heating;
DOI:10.1039/b110301f

Reference yield: 45.0%

: 61764-71-4
methyl propargyl carbonate

: 76005-94-2
2-chlorophenyl(phenyl)methanimine

: 92853-34-4
1-(2-chlorophenyl)-3-methylisoquinoline

Guidance literature:: With bromopentacarbonylmanganese(I); triphenylborane; sodium acetate; In 1,2-dimethoxyethane; at 90 ℃; for 24h; regioselective reaction; Inert atmosphere; Schlenk technique; Glovebox; Sealed tube;
DOI:10.1002/anie.201707396