2H-Benzimidazol-2-one, 1,3-dihydro-5-chloro-3-(4-hydroxyphenyl)-1-methyl-

Base Information

Chemical Name:2H-Benzimidazol-2-one, 1,3-dihydro-5-chloro-3-(4-hydroxyphenyl)-1-methyl-
CAS No.:79759-68-5
Molecular Formula:C14H11ClN2O2
Molecular Weight:274.7023
Hs Code.:
DSSTox Substance ID:DTXSID30229888
Wikidata:Q83110260

Synonyms:BRN 5575530;2H-Benzimidazol-2-one, 1,3-dihydro-5-chloro-3-(4-hydroxyphenyl)-1-methyl-;79759-68-5;1,3-Dihydro-5-chloro-3-(4-hydroxyphenyl)-1-methyl-2H-benzimidazol-2-one;DTXSID30229888;LS-33313

Suppliers and Price of 2H-Benzimidazol-2-one, 1,3-dihydro-5-chloro-3-(4-hydroxyphenyl)-1-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2H-Benzimidazol-2-one, 1,3-dihydro-5-chloro-3-(4-hydroxyphenyl)-1-methyl-

Chemical Property:

Vapor Pressure:8.43E-10mmHg at 25°C
Boiling Point:479°Cat760mmHg
Flash Point:243.5°C
Density:1.432g/cm³
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:274.0509053
Heavy Atom Count:19
Complexity:357

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=C(C=C(C=C2)Cl)N(C1=O)C3=CC=C(C=C3)O

Technology Process of 2H-Benzimidazol-2-one, 1,3-dihydro-5-chloro-3-(4-hydroxyphenyl)-1-methyl-

There total 7 articles about 2H-Benzimidazol-2-one, 1,3-dihydro-5-chloro-3-(4-hydroxyphenyl)-1-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 79759-85-6
3-(4-Benzyloxy-phenyl)-5-chloro-1-methyl-1,3-dihydro-benzoimidazol-2-one

: 79759-68-5
5-Chloro-3-(4-hydroxy-phenyl)-1-methyl-1,3-dihydro-benzoimidazol-2-one

Guidance literature:: With hydrogen; palladium on activated charcoal; In acetic acid; Ambient temperature;

Reference yield:

: 6373-46-2
p-benzyloxyaniline

: 79759-68-5
5-Chloro-3-(4-hydroxy-phenyl)-1-methyl-1,3-dihydro-benzoimidazol-2-one

Guidance literature:: Multi-step reaction with 6 steps

1: 47 percent / ethanol / 16 h / Ambient temperature

2: 95 percent / 37 percent aq. HCl, zinc powder / ethanol / 1 h

3: 71 percent / CHCl₃ / 5 h / Heating

4: 51 percent / EtONa / ethanol / 3 h / Heating

5: 73 percent / NaOH / methanol / 10 h / Ambient temperature

6: 83 percent / hydrogen / 10 percent Pd/C / acetic acid / Ambient temperature

With hydrogenchloride; sodium hydroxide; hydrogen; sodium ethanolate; zinc; palladium on activated charcoal; In methanol; ethanol; chloroform; acetic acid;

Reference yield:

: 610-40-2
3,4-dinitro-chlorobenzene

: 79759-68-5
5-Chloro-3-(4-hydroxy-phenyl)-1-methyl-1,3-dihydro-benzoimidazol-2-one

Guidance literature:: Multi-step reaction with 6 steps

1: 47 percent / ethanol / 16 h / Ambient temperature

2: 95 percent / 37 percent aq. HCl, zinc powder / ethanol / 1 h

3: 71 percent / CHCl₃ / 5 h / Heating

4: 51 percent / EtONa / ethanol / 3 h / Heating

5: 73 percent / NaOH / methanol / 10 h / Ambient temperature

6: 83 percent / hydrogen / 10 percent Pd/C / acetic acid / Ambient temperature

With hydrogenchloride; sodium hydroxide; hydrogen; sodium ethanolate; zinc; palladium on activated charcoal; In methanol; ethanol; chloroform; acetic acid;