2,4-Diamino-6-chloropyrimidine-5-carbaldehyde

Base Information

Chemical Name:2,4-Diamino-6-chloropyrimidine-5-carbaldehyde
CAS No.:18740-20-0
Molecular Formula:C₅H₅ClN₄O
Molecular Weight:172.574
Hs Code.:
NSC Number:103519
DSSTox Substance ID:DTXSID80295639
Wikidata:Q82035674

Synonyms:2,4-diamino-6-chloropyrimidine-5-carbaldehyde;18740-20-0;NSC103519;NCIOpen2_001746;SCHEMBL6364307;DTXSID80295639;NSC-103519

Suppliers and Price of 2,4-Diamino-6-chloropyrimidine-5-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2,4-Diamino-6-chloropyrimidine-5-carbaldehyde

Chemical Property:

Vapor Pressure:1.03E-09mmHg at 25°C
Boiling Point:489.1°Cat760mmHg
Flash Point:249.6°C
Density:1.658g/cm³
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:172.0151885
Heavy Atom Count:11
Complexity:155

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(=O)C1=C(N=C(N=C1Cl)N)N

Technology Process of 2,4-Diamino-6-chloropyrimidine-5-carbaldehyde

There total 1 articles about 2,4-Diamino-6-chloropyrimidine-5-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 18740-20-0
2,4-diamino-6-chloropyrimidine-5-carbaldehyde

Guidance literature:: 2-Amino-4,6-dichlor-pyrimidin-carbaldehyd-(5), NH3, A.;
DOI:10.1021/jm00308a054

Reference yield:

: 18740-20-0
2,4-diamino-6-chloropyrimidine-5-carbaldehyde

: 2,4-diamino-thieno[2,3-d]pyrimidine-6-carboxylic acid (4-methoxy-phenyl)-amide

Guidance literature:: Multi-step reaction with 3 steps

1: 72 percent / 4 Angstroem MS; K₂CO₃ / dimethylformamide / 2 h / 60 °C

2: NaOH; water / methanol / Heating

3: 75 percent / N,N'-dicyclohexylcarbodiimide; 1H-1,2,3-benzotriazol-1-ol / dimethylformamide / 60 h / 20 °C

With sodium hydroxide; 4 Angstroem MS; water; potassium carbonate; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In methanol; N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570430630

Reference yield:

: 18740-20-0
2,4-diamino-6-chloropyrimidine-5-carbaldehyde

: 2,4-diamino-thieno[2,3-d]pyrimidine-6-carboxylic acid (3,4,5-trimethoxy-phenyl)-amide

Guidance literature:: Multi-step reaction with 3 steps

1: 72 percent / 4 Angstroem MS; K₂CO₃ / dimethylformamide / 2 h / 60 °C

2: NaOH; water / methanol / Heating

3: 49 percent / N,N'-dicyclohexylcarbodiimide; 1H-1,2,3-benzotriazol-1-ol / dimethylformamide / 24 h / 20 °C

With sodium hydroxide; 4 Angstroem MS; water; potassium carbonate; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In methanol; N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570430630