2,4-ditert-butyl-1-nitrobenzene

Base Information

• Chemical Name: 2,4-ditert-butyl-1-nitrobenzene
• CAS No.: 93720-37-7
• Molecular Formula: C14H21NO2
• Molecular Weight: 235.326
• Mol file: 93720-37-7.mol

Synonyms:2,4-Di-t.-butyl-nitrobenzol;2,4-Di-tert-butyl-1-nitro-benzol;2,4-di-tert-butylnitrobenzene;4-nitro-m-di-tert-butylbenzene;2,4-di-tert-butyl-1-nitro-benzene;

Chemical Property of 2,4-ditert-butyl-1-nitrobenzene

Chemical Property:

• PSA: 45.82000
• LogP: 4.71300

Purity/Quality:

2,4-DITERT-BUTYL-1-NITROBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-ditert-butyl-1-nitrobenzene

There total 4 articles about 2,4-ditert-butyl-1-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

1,3-di-tert-butylbenzene (1014-60-4) → 2,4-di-tert-butyl-1-nitrobenzene (93720-37-7)

Guidance literature:

With ammonium nitrate; trifluoroacetic acid; for 2h; Inert atmosphere;

DOI:10.1002/anie.202007595

Reference yield:

benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 2,4-di-tert-butyl-1-nitrobenzene (93720-37-7)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl; AlCl₃ / 60 °C / Einleiten von Isobutylen

2: nitric acid

With hydrogenchloride; aluminium trichloride; nitric acid;

DOI:10.1021/ja01201a001

Reference yield:

3,5-di-tert-butyl-2-nitroaniline (60190-51-4) → 2,4-di-tert-butyl-1-nitrobenzene (93720-37-7)

Guidance literature:

With sulfuric acid; acetic acid; sodium nitrite; at 0 ℃; Diazotization_.Reagens 4: wss. Hypophosphorigsaeure;

DOI:10.1177/001088040004100413

upstream raw materials:

1,3-di-tert-butylbenzene

3,5-di-tert-butyl-2-nitroaniline

benzene

Downstream raw materials:

4,6-di(t-butyl)-2-(diphenylphosphinoyloxy)-4-methylaniline

diphenyl-phosphinic acid

2,4-Di-tert-butylformanilid

2,4-bis(1,1-dimethylethyl)benzenamine