Benzenemethanol, a-methyl-2-(phenylmethoxy)-

Base Information

• Chemical Name: Benzenemethanol, a-methyl-2-(phenylmethoxy)-
• CAS No.: 94001-66-8
• Molecular Formula: C15H16O2
• Molecular Weight: 228.291
• Mol file: 94001-66-8.mol

Synonyms:1-(2-Benzyloxy-phenyl)-ethanol;1-(2-Benzyloxy-phenyl)-aethanol;1-(2-benzyloxyphenyl)-ethanol;α-(o-Benzyloxy-phenyl)-aethylalkohol;

Chemical Property of Benzenemethanol, a-methyl-2-(phenylmethoxy)-

Chemical Property:

• PSA: 29.46000
• LogP: 3.31890

Purity/Quality:

99% ^*data from raw suppliers

1-[2-(BENZYLOXY)PHENYL]ETHAN-1-OL ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenemethanol, a-methyl-2-(phenylmethoxy)-

There total 11 articles about Benzenemethanol, a-methyl-2-(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2'-benzyloxyacetophenone (31165-67-0) → 1-(2-benzyloxyphenyl)-1-ethanol (94001-66-8)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 20 ℃; for 2h;

DOI:10.1021/ol035786v

Reference yield:

o-hydroxyacetophenone (118-93-4,104809-67-8) → 1-(2-benzyloxyphenyl)-1-ethanol (94001-66-8)

Guidance literature:

With ethanol; nickel; Hydrogenation_.Erwaermen des Reaktionsprodukts mit Benzylchlorid und K₂CO₃ in Aceton;

Reference yield:

benzyl chloride (100-44-7) → 1-(2-benzyloxyphenyl)-1-ethanol (94001-66-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / K₂CO₃ / acetone / 12 h / Heating

2: 99 percent / NaBH₄ / ethanol / 2 h / 20 °C

With sodium tetrahydroborate; potassium carbonate; In ethanol; acetone;

DOI:10.1021/ol035786v

upstream raw materials:

o-hydroxyacetophenone

2'-benzyloxyacetophenone

benzyl chloride

benzyl alcohol

Downstream raw materials:

4-[1-(2-benzyloxy-phenyl)-ethoxy]-benzaldehyde

4-[1-(2-benzyloxy-phenyl)-ethoxy]-3,5-dimethoxy-benzaldehyde

{4-[1-(2-benzyloxy-phenyl)-ethoxy]-phenyl}-methanol

{4-[1-(2-benzyloxy-phenyl)-ethoxy]-3,5-dimethoxy-phenyl}-methanol