4-Hepten-3-one, 2-((2R,5R)-5-ethenyltetrahydro-5-methyl-2-furanyl)-6-hydroxy-6-methyl-, (2R,4E)-

Base Information

Chemical Name:4-Hepten-3-one, 2-((2R,5R)-5-ethenyltetrahydro-5-methyl-2-furanyl)-6-hydroxy-6-methyl-, (2R,4E)-
CAS No.:73395-08-1
Molecular Formula:C₁₅H₂₄O₃
Molecular Weight:252.354
Hs Code.:

Synonyms:4-Hepten-3-one, 2-((2R,5R)-5-ethenyltetrahydro-5-methyl-2-furanyl)-6-hydroxy-6-methyl-, (2R,4E)-;73395-08-1;NSC 362428

Suppliers and Price of 4-Hepten-3-one, 2-((2R,5R)-5-ethenyltetrahydro-5-methyl-2-furanyl)-6-hydroxy-6-methyl-, (2R,4E)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-Hepten-3-one, 2-((2R,5R)-5-ethenyltetrahydro-5-methyl-2-furanyl)-6-hydroxy-6-methyl-, (2R,4E)-

Chemical Property:

Vapor Pressure:7.35E-07mmHg at 25°C
Boiling Point:366.5°Cat760mmHg
Flash Point:127.7°C
Density:1.042g/cm³
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:252.17254462
Heavy Atom Count:18
Complexity:357

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1CCC(O1)(C)C=C)C(=O)C=CC(C)(C)O
Isomeric SMILES:C[C@H](C1CC[C@](O1)(C)C=C)C(=O)/C=C/C(C)(C)O

Technology Process of 4-Hepten-3-one, 2-((2R,5R)-5-ethenyltetrahydro-5-methyl-2-furanyl)-6-hydroxy-6-methyl-, (2R,4E)-

There total 4 articles about 4-Hepten-3-one, 2-((2R,5R)-5-ethenyltetrahydro-5-methyl-2-furanyl)-6-hydroxy-6-methyl-, (2R,4E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: C₇H₁₆O₂Si

: 1448011-58-2
dimethyl {(3S)-3-[(2S,5S)-5-methyl-5-vinyltetrahydrofuran-2-yl]-2-oxobutyl}phosphonate

: 54783-66-3,73395-08-1,88243-64-5,110269-54-0,133695-00-8
trans-Hydroxydavanone

Guidance literature:: With barium(II) hydroxide; In tetrahydrofuran; water; at 0 ℃; for 0.5h; stereoselective reaction; Inert atmosphere;
DOI:10.1055/s-0033-1338429

Reference yield:

: (E)-6-Hydroperoxy-6-methyl-2-(5-methyl-5-vinyl-tetrahydro-furan-2-yl)-hept-4-en-3-one

: 54783-66-3,73395-08-1,88243-64-5,110269-54-0,133695-00-8
(E)-6-Hydroxy-6-methyl-2-(5-methyl-5-vinyl-tetrahydro-furan-2-yl)-hept-4-en-3-one

Guidance literature:: With triphenylphosphine; In chloroform-d1; for 0.25h;
DOI:10.1016/S0031-9422(00)80280-0

Reference yield:

: 1448011-56-0
ethyl (2S)-2-[(2S,5S)-5-methyl-5-vinyltetrahydrofuran-2-yl]propanoate

: 54783-66-3,73395-08-1,88243-64-5,110269-54-0,133695-00-8
trans-Hydroxydavanone

Guidance literature:: Multi-step reaction with 3 steps

1.1: isopropylmagnesium chloride / tetrahydrofuran / -20 °C / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.62 h / -78 - 0 °C / Inert atmosphere

2.2: 1.03 h / 0 °C / Inert atmosphere

3.1: barium(II) hydroxide / tetrahydrofuran; water / 0.5 h / 0 °C / Inert atmosphere

With n-butyllithium; isopropylmagnesium chloride; barium(II) hydroxide; In tetrahydrofuran; hexane; water; 3.1: |Horner-Wadsworth-Emmons Olefination;
DOI:10.1055/s-0033-1338429