2-Amino-4-(3,7-dimethylimidazo[1,2-a]pyridin-2-yl)phenol

Base Information

Chemical Name:2-Amino-4-(3,7-dimethylimidazo[1,2-a]pyridin-2-yl)phenol
CAS No.:94662-29-0
Molecular Formula:C15H15N3O
Molecular Weight:253.304
Hs Code.:
DSSTox Substance ID:DTXSID90552523
Wikidata:Q82432833

Synonyms:94662-29-0;2-Amino-4-(3,7-dimethylimidazo[1,2-a]pyridin-2-yl)phenol;SCHEMBL10651725;DTXSID90552523;GKKUBAILLKPTHQ-UHFFFAOYSA-N;3,7-dimethyl-2-(3-amino-4-hydro-xyphenyl)imidazo[1,2-a]pyridine;3,7-dimethyl-2-(3-amino-4-hydroxyphenyl)imidazo[1,2-a]pyridine

Suppliers and Price of 2-Amino-4-(3,7-dimethylimidazo[1,2-a]pyridin-2-yl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-Amino-4-(3,7-dimethylimidazo[1,2-a]pyridin-2-yl)phenol

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:253.121512110
Heavy Atom Count:19
Complexity:325

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=NC(=C(N2C=C1)C)C3=CC(=C(C=C3)O)N

Technology Process of 2-Amino-4-(3,7-dimethylimidazo[1,2-a]pyridin-2-yl)phenol

There total 5 articles about 2-Amino-4-(3,7-dimethylimidazo[1,2-a]pyridin-2-yl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.9%

: 94662-28-9
3,7-Dimethyl-2-(4-hydroxy-3-nitrophenyl)imidazo<1,2-a>pyridine

: 94662-29-0
2-(3-Amino-4-hydroxyphenyl)-3,7-dimethylimidazo<1,2-a>pyridine

Guidance literature:: With hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol; under 760 Torr; Ambient temperature;
DOI:10.1248/cpb.39.2937

Reference yield:

: 695-34-1
2-Amino-4-methylpyridine

: 94662-29-0
2-(3-Amino-4-hydroxyphenyl)-3,7-dimethylimidazo<1,2-a>pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 35.9 percent / Et₃N / tetrahydrofuran / 1.) r.t., 2.) 60-70 deg C

2: 53.9 percent / hydrogen / 10 percent Pd-C / ethanol; tetrahydrofuran / 760 Torr / Ambient temperature

With hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol;
DOI:10.1248/cpb.39.2937

Reference yield:

: 50916-44-4
1-(4-hydroxy-3-nitrophenyl)propan-1-one

: 94662-29-0
2-(3-Amino-4-hydroxyphenyl)-3,7-dimethylimidazo<1,2-a>pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 94.1 percent / pyridinium bromide perbromide, 30 percent HBr-AcOH / acetic acid / 1 h / Ambient temperature

2: 35.9 percent / Et₃N / tetrahydrofuran / 1.) r.t., 2.) 60-70 deg C

3: 53.9 percent / hydrogen / 10 percent Pd-C / ethanol; tetrahydrofuran / 760 Torr / Ambient temperature

With hydrogen bromide; hydrogen; pyridinium hydrobromide perbromide; acetic acid; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol; acetic acid;
DOI:10.1248/cpb.39.2937