3-(tert-Butyl)-5,7-dichloroimidazo[1,5-c]pyrimidine

Base Information

Chemical Name:3-(tert-Butyl)-5,7-dichloroimidazo[1,5-c]pyrimidine
CAS No.:94694-13-0
Molecular Formula:C₁₀H₁₁Cl₂N₃
Molecular Weight:244.123
Hs Code.:
DSSTox Substance ID:DTXSID90538706
Wikidata:Q82414199

Synonyms:94694-13-0;3-(tert-Butyl)-5,7-dichloroimidazo[1,5-c]pyrimidine;3-tert-Butyl-5,7-dichloroimidazo[1,5-c]pyrimidine;SCHEMBL10843900;DTXSID90538706

Suppliers and Price of 3-(tert-Butyl)-5,7-dichloroimidazo[1,5-c]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-(tert-Butyl)-5,7-dichloroimidazo[1,5-c]pyrimidine 97%
1g
$ 686.00

Alichem
3-(Tert-butyl)-5,7-dichloroimidazo[1,5-c]pyrimidine
1g
$ 737.30

Total 3 raw suppliers

Chemical Property of 3-(tert-Butyl)-5,7-dichloroimidazo[1,5-c]pyrimidine

Chemical Property:

PSA：30.19000
LogP:3.33360
XLogP3:4.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:243.0330028
Heavy Atom Count:15
Complexity:241

Purity/Quality:: 3-(tert-Butyl)-5,7-dichloroimidazo[1,5-c]pyrimidine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=NC=C2N1C(=NC(=C2)Cl)Cl

Technology Process of 3-(tert-Butyl)-5,7-dichloroimidazo[1,5-c]pyrimidine

There total 4 articles about 3-(tert-Butyl)-5,7-dichloroimidazo[1,5-c]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 94694-12-9
N-(2,6-Dioxo-1,2,3,6-tetrahydro-pyrimidin-4-ylmethyl)-2,2-dimethyl-propionamide

: 108222-63-5
3-tert-Butyl-7-chloro-6H-imidazo[1,5-c]pyrimidin-5-one

: 94694-13-0
5,7-dichloro-3-(t-butyl)imidazo[1,5-c]pyrimidine

Guidance literature:: With trichlorophosphate; 1.) 75 deg C, 4 h, 2.) reflux, 16 h;;
DOI:10.1002/jhet.5570230402

Reference yield:

: 18592-13-7
6-chloromethyluracil

: 94694-13-0
5,7-dichloro-3-(t-butyl)imidazo[1,5-c]pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / NH₃ / 18 h / Ambient temperature

2: 78 percent / triethylamine / dimethylformamide / 3 h / 130 - 150 °C

3: 39 percent / POCl₃ / 1.) 75 deg C, 4 h, 2.) reflux, 16 h;

With ammonia; triethylamine; trichlorophosphate; In N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570230402

Reference yield:

: 20989-02-0
6-aminomethylpyrimidine-2,4-dione

: 94694-13-0
5,7-dichloro-3-(t-butyl)imidazo[1,5-c]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / triethylamine / dimethylformamide / 3 h / 130 - 150 °C

2: 39 percent / POCl₃ / 1.) 75 deg C, 4 h, 2.) reflux, 16 h;

With triethylamine; trichlorophosphate; In N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570230402