Technology Process of Murrayafoline B
There total 16 articles about Murrayafoline B which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 18h;
Inert atmosphere;
Reflux;
DOI:10.1055/s-0036-1588322
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 2.5 g / 48percent HBr / 4 h / 135 - 140 °C
2: 950 mg / pyridine / 6 h / 125 - 130 °C
3: 1.) BF3 etherate / 1.) dioxane, room temperature, 10 min, 2.) dioxane, room temperature, 1h
4: 35 mg / K2CO3 / acetone / 4 h / Ambient temperature
5: 20 mg / NaOMe / methanol / 0.25 h / Ambient temperature
With
pyridine; boron trifluoride diethyl etherate; hydrogen bromide; sodium methylate; potassium carbonate;
In
methanol; acetone;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) BF3 etherate / 1.) dioxane, room temperature, 10 min, 2.) dioxane, room temperature, 1h
2: 35 mg / K2CO3 / acetone / 4 h / Ambient temperature
3: 20 mg / NaOMe / methanol / 0.25 h / Ambient temperature
With
boron trifluoride diethyl etherate; sodium methylate; potassium carbonate;
In
methanol; acetone;
