1,8-Dichloro-9-methoxyanthracene

Base Information

• Chemical Name: 1,8-Dichloro-9-methoxyanthracene
• CAS No.: 98797-46-7
• Molecular Formula: C₁₅H₁₀Cl₂O
• Molecular Weight: 277.15
• European Community (EC) Number: 684-974-8
• DSSTox Substance ID: DTXSID40391904
• Nikkaji Number: J3.168.219C
• Mol file: 98797-46-7.mol

Synonyms:1,8-dichloro-9-methoxyanthracene;98797-46-7;1,8-dichloro-9-methoxy-anthracene;Anthracene, 1,8-dichloro-9-methoxy-;BIDD:GT0856;DTXSID40391904;AKOS024330678

Chemical Property of 1,8-Dichloro-9-methoxyanthracene

Chemical Property:

• PSA: 9.23000
• LogP: 5.30840
• XLogP3: 5.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 276.0108703
• Heavy Atom Count: 18
• Complexity: 270

Purity/Quality:

1,8-DICHLORO-9-METHOXY-ANTHRACENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=C2C(=CC3=C1C(=CC=C3)Cl)C=CC=C2Cl

Technology Process of 1,8-Dichloro-9-methoxyanthracene

There total 3 articles about 1,8-Dichloro-9-methoxyanthracene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1,8-dichloro-9,10-dihydroanthracen-9-one (50259-93-3) + dimethyl sulfate (77-78-1) → 1,8-dichloro-9-methoxyanthracene (98797-46-7)

Guidance literature:

With sodium hydroxide; In ethanol;

DOI:10.1246/bcsj.58.1690

Reference yield:

1,8-dichloroanthraquinone (82-43-9) → 1,8-dichloro-9-methoxyanthracene (98797-46-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / conc. sulfuric acid, Al / 8 h / 25 - 30 °C

2: aq. NaOH, (n-Bu)4NBr / CH₂Cl₂ / 2 h / 25 °C

With sodium hydroxide; sulfuric acid; tetrabutylammomium bromide; aluminium; In dichloromethane;

DOI:10.1021/jo00356a031

Reference yield:

1,8-dichloro-9,10-dihydroanthracen-9-one (50259-93-3) → 1,8-dichloro-9-methoxyanthracene (98797-46-7)

Guidance literature:

upstream raw materials:

1,8-dichloro-9,10-dihydroanthracen-9-one

dimethyl sulfate

1,8-dichloroanthraquinone