Phenoxy(pyrrolidin-2-yl)phosphinic acid

Base Information

• Chemical Name: Phenoxy(pyrrolidin-2-yl)phosphinic acid
• CAS No.: 99305-82-5
• Molecular Formula: C₁₀H₁₄NO₃P
• Molecular Weight: 227.2
• European Community (EC) Number: 810-892-0
• Nikkaji Number: J2.331.627G
• Mol file: 99305-82-5.mol

Synonyms:phenoxy(pyrrolidin-2-yl)phosphinic acid;99305-82-5;Pyrrolidine-2-phosphonic acid phenyl mono ester;SCHEMBL459085;MFCD16876775;AKOS017344984;phenyl hydrogen pyrrolidin-2-yl-phosphonate

Chemical Property of Phenoxy(pyrrolidin-2-yl)phosphinic acid

Chemical Property:

• Melting Point: 123-125 °C (methanol)
• Boiling Point: 377.6±52.0 °C (760 mmHg)
• PKA: 0.83±0.20(Predicted)
• PSA: 68.37000
• Density: 1.29±0.1 g/cm3 (20 °C, 760 mmHg)
• LogP: 2.28910
• XLogP3: -1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 227.07113031
• Heavy Atom Count: 15
• Complexity: 253

Purity/Quality:

98.5% ^*data from raw suppliers

Pyrrolidine-2-phosphonicAcidPhenylMonoEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(NC1)P(=O)(O)OC2=CC=CC=C2

Technology Process of Phenoxy(pyrrolidin-2-yl)phosphinic acid

There total 1 articles about Phenoxy(pyrrolidin-2-yl)phosphinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diphenyl pyrrolidine-2-phosphonate hydrochloride → pyrrolidine-2-phosphonic acid phenyl monoester (99305-82-5)

Guidance literature:

With lithium hydroxide; In acetonitrile; for 3h;

DOI:10.1002/chem.200501473

Refernces