(Z)-N'-hydroxycyclopent-1-carboximidamide

Base Information

• Chemical Name: (Z)-N'-hydroxycyclopent-1-carboximidamide
• CAS No.: 99623-12-8
• Molecular Formula: C6H12N2O
• Molecular Weight: 128.174
• Hs Code.: 2925290090
• European Community (EC) Number: 877-566-8
• DSSTox Substance ID: DTXSID50912588
• Mol file: 99623-12-8.mol

Synonyms:N'-hydroxycyclopentanecarboximidamide;99623-12-8;1942923-13-8;N-Hydroxycyclopentanecarboximidamide;(Z)-N'-hydroxycyclopent-1-carboximidamide;(Z)-N'-hydroxycyclopentanecarboximidamide;SCHEMBL1277640;n-hydroxycyclopentanecarboxamidine;DTXSID50912588;MFCD03426265;AKOS000152723;KS-7408;CS-0368544;EN300-40814;N-hydroxycyclopentanecarboximidamide, AldrichCPR;F2185-0202;Z285132798

Chemical Property of (Z)-N'-hydroxycyclopent-1-carboximidamide

Chemical Property:

• Boiling Point: 277.2oC at 760 mmHg
• Flash Point: 121.5oC
• PSA: 56.11000
• Density: 1.29g/cm3
• LogP: 1.62330
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 128.094963011
• Heavy Atom Count: 9
• Complexity: 116

Purity/Quality:

98% ^*data from raw suppliers

(Z)-N''-hydroxycyclopent-1-carboximidamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(C1)C(=NO)N
• Isomeric SMILES: C1CCC(C1)/C(=N/O)/N

Technology Process of (Z)-N'-hydroxycyclopent-1-carboximidamide

There total 3 articles about (Z)-N'-hydroxycyclopent-1-carboximidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

cyclopentanecarbonitrile (4254-02-8) → N’-hydroxycyclopentanecarboximidamide (99623-12-8)

Guidance literature:

With hydroxylamine hydrochloride; sodium ethanolate; In ethanol; at 25 - 90 ℃; for 16h;

Reference yield:

cyclopentanecarbonitrile (4254-02-8) → N-hydroxycyclopentanecarboxamidine (99623-12-8)

Guidance literature:

With hydroxylamine hydrochloride; potassium carbonate; In methanol; at 80 ℃; for 5h;

Reference yield:

→ N-hydroxycyclopentanecarboxamidine (99623-12-8)

Guidance literature:

With hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine; In ethanol; Reflux;

upstream raw materials:

cyclopentanecarbonitrile

Downstream raw materials:

C₃₀H₃₅N₅O₄

Refernces

• 1、 -. "HETEROARYLBENZIMIDAZOLE COMPOUNDS". Page/Page column 383; 384. . Retrieved 2017/07/06.
• 2、 -. "COMPOUNDS HAVING AN ETHR INHIBITING ACTIVITY - USE OF SAID COMPOUNDS AS DRUGS - PHARMACEUTICAL COMPOSITION AND PRODUCT CONTAINING SAID COMPOUNDS". Page/Page column 10. . Retrieved 2013/05/21.