5-nitro-N-(1,3-thiazol-2-yl)furan-2-carboxamide

Base Information

Chemical Name:5-nitro-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS No.:99768-68-0
Molecular Formula:C₈H₅N₃O₄S
Molecular Weight:239.211
Hs Code.:
DSSTox Substance ID:DTXSID60356419
Wikidata:Q82135740
Mol file:99768-68-0.mol

Synonyms:5-nitro-N-(1,3-thiazol-2-yl)furan-2-carboxamide;99768-68-0;2-Furancarboxamide, 5-nitro-N-2-thiazolyl-;Oprea1_430761;Oprea1_598754;SCHEMBL22823076;DTXSID60356419;STK095259;AKOS000668761;5-nitro-N-(1,3-thiazol-2-yl)-2-furamide;SR-01000414019;SR-01000414019-1

Suppliers and Price of 5-nitro-N-(1,3-thiazol-2-yl)furan-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-nitro-N-(1,3-thiazol-2-yl)furan-2-carboxamide

Chemical Property:

PSA：129.19000
LogP:2.49280
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:239.00007682
Heavy Atom Count:16
Complexity:296

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CSC(=N1)NC(=O)C2=CC=C(O2)[N+](=O)[O-]

Technology Process of 5-nitro-N-(1,3-thiazol-2-yl)furan-2-carboxamide

There total 3 articles about 5-nitro-N-(1,3-thiazol-2-yl)furan-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 96-50-4
2-thiazolylamine

: 25084-14-4
5-nitrofuran-2-carboxylic chloride

: 99768-68-0
N-(thiazol-2-yl)-5-nitrofuran-2-carboxamide

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; Cooling with ice;

Reference yield:

: 96-50-4
2-thiazolylamine

: 645-12-5
5-nitro-2-furoic acid

: 99768-68-0
N-(thiazol-2-yl)-5-nitrofuran-2-carboxamide

Guidance literature:: 5-nitro-2-furoic acid; With thionyl chloride; for 5h; Reflux;

2-thiazolylamine; With pyridine; at 20 ℃;
DOI:10.1038/s41419-021-04191-9