Ethyl 4-nitro-3-phenyl-1,2-oxazole-5-carboxylate

Base Information

Chemical Name:Ethyl 4-nitro-3-phenyl-1,2-oxazole-5-carboxylate
CAS No.:99934-18-6
Molecular Formula:C12H10N2O5
Molecular Weight:262.222
Hs Code.:
DSSTox Substance ID:DTXSID50542006
Nikkaji Number:J283.760I
Wikidata:Q82418511

Synonyms:99934-18-6;Ethyl 4-nitro-3-phenyl-1,2-oxazole-5-carboxylate;5-Isoxazolecarboxylic acid, 4-nitro-3-phenyl-, ethyl ester;Ethyl 4-nitro-3-phenylisoxazole-5-carboxylate;SCHEMBL1753170;DTXSID50542006;ITASWOKRHADEDM-UHFFFAOYSA-N;4-nitro-3-phenyl-isoxazole-5-carboxylic acid ethyl ester

Suppliers and Price of Ethyl 4-nitro-3-phenyl-1,2-oxazole-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Ethyl 4-nitro-3-phenyl-1,2-oxazole-5-carboxylate

Chemical Property:

Boiling Point:117-118 °C(Press: 0.04 Torr)
PSA：98.15000
Density:1.331±0.06 g/cm3(Predicted)
LogP:2.94970
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:262.05897142
Heavy Atom Count:19
Complexity:338

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(C(=NO1)C2=CC=CC=C2)[N+](=O)[O-]

Technology Process of Ethyl 4-nitro-3-phenyl-1,2-oxazole-5-carboxylate

There total 2 articles about Ethyl 4-nitro-3-phenyl-1,2-oxazole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.6%

: ethyl oxo<<(1-phenyl-2-nitroethylidene)amino>oxy>acetate

: 99934-18-6
ethyl 4-nitro-3-phenylizoxazole-5-carboxylate

Guidance literature:: With 4 A molecular sieve; triethylamine; In dichloromethane; for 50h; Ambient temperature;

Reference yield:

: 21205-24-3
2-isonitroso-1-nitro-2-phenylethane

: 99934-18-6
ethyl 4-nitro-3-phenylizoxazole-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 92.8 percent / diethyl ether / 17 h / Ambient temperature

2: 99.6 percent / triethylamine, molecular sieves 4A / CH₂Cl₂ / 50 h / Ambient temperature

With 4 A molecular sieve; triethylamine; In diethyl ether; dichloromethane;