4(3H)-Quinazolinone, 2-(aminomethyl)-5-methyl-3-(2-methylphenyl)-

Base Information

Chemical Name:4(3H)-Quinazolinone, 2-(aminomethyl)-5-methyl-3-(2-methylphenyl)-
CAS No.:371244-07-4
Molecular Formula:C17H17N3O
Molecular Weight:279.341
Hs Code.:
Mol file:371244-07-4.mol

Synonyms:4(3H)-Quinazolinone, 2-(aminomethyl)-5-methyl-3-(2-methylphenyl)-;

Suppliers and Price of 4(3H)-Quinazolinone, 2-(aminomethyl)-5-methyl-3-(2-methylphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of 4(3H)-Quinazolinone, 2-(aminomethyl)-5-methyl-3-(2-methylphenyl)-

Chemical Property:

Boiling Point:463.4±55.0 °C(Predicted)
PKA:8.06±0.29(Predicted)
PSA：60.91000
Density:1.22±0.1 g/cm3(Predicted)
LogP:3.16150

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

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Hazard Codes:

MSDS Files:

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Technology Process of 4(3H)-Quinazolinone, 2-(aminomethyl)-5-methyl-3-(2-methylphenyl)-

There total 5 articles about 4(3H)-Quinazolinone, 2-(aminomethyl)-5-methyl-3-(2-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₂H₂₇N₃O₃

: 371244-07-4
2-(aminomethyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one

Guidance literature:: With Octanethiol; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 20 ℃;

Reference yield:

: 371244-11-0
2-(chloromethyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one

: 371244-07-4
2-(aminomethyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one

Guidance literature:: 2-(chloromethyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one; With sodium azide; In N,N-dimethyl-formamide; at 20 ℃; for 0.25h;

With ammonium formate; palladium 10% on activated carbon; In methanol; at 80 ℃; for 0.5h;

Reference yield:

: 2-amino-6-methylbenzoyl chloride

: 371244-07-4
2-(aminomethyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: tetrahydrofuran / 2 h / 0 - 80 °C

2.1: acetic acid / 0.25 h / 120 °C

3.1: sodium azide / N,N-dimethyl-formamide / 0.25 h / 20 °C

3.2: 0.5 h / 80 °C

With sodium azide; acetic acid; In tetrahydrofuran; N,N-dimethyl-formamide;