(S)-1,3-Dibenzylpiperazine-2,5-dione

Base Information

Chemical Name:(S)-1,3-Dibenzylpiperazine-2,5-dione
CAS No.:169447-84-1
Molecular Formula:C18H18N2O2
Molecular Weight:294.353
Hs Code.:
DSSTox Substance ID:DTXSID60443853
Nikkaji Number:J2.791.726G
Wikidata:Q82261826

Synonyms:(S)-1,3-Dibenzylpiperazine-2,5-dione;169447-84-1;(3S)-1,3-dibenzylpiperazine-2,5-dione;SCHEMBL8452072;DTXSID60443853;CUSGSDUYPXBYHI-INIZCTEOSA-N;AKOS015917609;1,3(S)-Dibenzylpiperazine-2,5-dione;1,3alpha-Dibenzylpiperazine-2,5-dione;F12509

Suppliers and Price of (S)-1,3-Dibenzylpiperazine-2,5-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of (S)-1,3-Dibenzylpiperazine-2,5-dione

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:294.136827821
Heavy Atom Count:22
Complexity:398

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)NC(C(=O)N1CC2=CC=CC=C2)CC3=CC=CC=C3
Isomeric SMILES:C1C(=O)N[C@H](C(=O)N1CC2=CC=CC=C2)CC3=CC=CC=C3

Technology Process of (S)-1,3-Dibenzylpiperazine-2,5-dione

There total 16 articles about (S)-1,3-Dibenzylpiperazine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 2382-86-7,106109-98-2,2537-00-0
methyl (S)-2-(2-chloroacetamido)-3-phenylpropanoate

: 100-46-9
benzylamine

: 169447-84-1
(3S)-1,3-dibenzylpiperazine-2,5-dione

Guidance literature:: With triethylamine; In methanol; for 20h; Reflux;
DOI:10.1021/ol8002749

Reference yield:

: 2382-86-7,106109-98-2,2537-00-0
methyl (S)-2-(2-chloroacetamido)-3-phenylpropanoate

: 100-46-9
benzylamine

: 208840-35-1
1-Benzyl-3(R)-(benzyl)-piperazine-2,5-dione

: 169447-84-1
(3S)-1,3-dibenzylpiperazine-2,5-dione

Guidance literature:: With triethylamine; In butan-1-ol; at 180 ℃; for 0.5h; Overall yield = 572 mg; Sealed tube; Microwave irradiation;
DOI:10.1080/00397911.2019.1671983