(R)-2-Aminomethyl-4-Boc-morpholine

Base Information

Chemical Name:(R)-2-Aminomethyl-4-Boc-morpholine
CAS No.:1174913-80-4
Molecular Formula:C10H20N2O3
Molecular Weight:216.28
Hs Code.:2934999090
DSSTox Substance ID:DTXSID40363929
Wikidata:Q72439714
Mol file:1174913-80-4.mol

Synonyms:1174913-80-4;(R)-2-Aminomethyl-4-Boc-morpholine;tert-butyl (2R)-2-(aminomethyl)morpholine-4-carboxylate;(R)-TERT-BUTYL 2-(AMINOMETHYL)MORPHOLINE-4-CARBOXYLATE;MFCD13189480;(R)-4-Boc-2-(aminomethyl)morpholine;(R)-N-BOC-2-AMINOMETHYLMORPHOLINE;SCHEMBL555079;DTXSID40363929;CS-M3423;AM9590;4-Morpholinecarboxylicacid,2-(aminomethyl)-,1,1-dimethylethylester,(2R);AKOS016843021;4-MORPHOLINECARBOXYLIC ACID, 2-(AMINOMETHYL)-, 1,1-DIMETHYLETHYL ESTER, (2R)-;AS-35732;EN300-5250736;tert-butyl (R)-2-aminomethylmorpholin-4-carboxylate;(R)-TERT-BUTYL2-(AMINOMETHYL)MORPHOLINE-4-CARBOXYLATE;1,1-dimethylethyl (2R)-2-(aminomethyl)-4-morpholinecarboxylate

Suppliers and Price of (R)-2-Aminomethyl-4-Boc-morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-2-Aminomethyl-4-boc-morpholine
100mg
$ 285.00

SynQuest Laboratories
(R)-4-Boc-2-(aminomethyl)morpholine
500 mg
$ 695.00

Matrix Scientific
(R)-2-Aminomethyl-4-Boc-morpholine 97.0%
1g
$ 1073.00

Crysdot
(R)-tert-Butyl2-(aminomethyl)morpholine-4-carboxylate 95+%
1g
$ 183.00

Chemenu
tert-butyl(2R)-2-(aminomethyl)morpholine-4-carboxylate 97%
1g
$ 418.00

Chemenu
tert-butyl(2R)-2-(aminomethyl)morpholine-4-carboxylate 97%
5g
$ 1298.00

Apolloscientific
(R)-4-Boc-2-(aminomethyl)morpholine
500mg
$ 841.00

Ambeed
(R)-tert-Butyl2-(aminomethyl)morpholine-4-carboxylate 97%
250mg
$ 94.00

Ambeed
(R)-tert-Butyl2-(aminomethyl)morpholine-4-carboxylate 97%
5g
$ 762.00

Ambeed
(R)-tert-Butyl2-(aminomethyl)morpholine-4-carboxylate 97%
1g
$ 221.00

Total 37 raw suppliers

Chemical Property of (R)-2-Aminomethyl-4-Boc-morpholine

Chemical Property:

Boiling Point:310.7 °C at 760 mmHg
PKA:9.37±0.29(Predicted)
Flash Point:141.7 °C
PSA：64.79000
Density:1.078 g/cm³
LogP:1.21920
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:-0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:216.14739250
Heavy Atom Count:15
Complexity:225

Purity/Quality:

99%, ^*data from raw suppliers

(R)-2-Aminomethyl-4-boc-morpholine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCOC(C1)CN
Isomeric SMILES:CC(C)(C)OC(=O)N1CCO[C@@H](C1)CN

Technology Process of (R)-2-Aminomethyl-4-Boc-morpholine

There total 7 articles about (R)-2-Aminomethyl-4-Boc-morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1132683-15-8
tert-butyl (2S)-2-(azidomethyl)morpholine-4-carboxylate

: 1174913-80-4
tert-butyl (2R)-2-(aminomethyl)morpholine-4-carboxylate

Guidance literature:: With palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; for 24h; Inert atmosphere;

Reference yield: 73.0%

: 1308849-93-5
(R)-tert-butyl 2-((1,3-dioxoisoindolin-2-yl)methyl)morpholine-4-carboxylate

: 1174913-80-4
tert-butyl (2R)-2-(aminomethyl)morpholine-4-carboxylate

Guidance literature:: With ethanolamine; at 20 ℃; for 16h;

Reference yield:

: 135065-76-8
tert-butyl (2S)-2-(hydroxymethyl)morpholine-4-carboxylate

: 1174913-80-4
tert-butyl (2R)-2-(aminomethyl)morpholine-4-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 1.5 h / 0 - 20 °C

2: N,N-dimethyl-formamide / 16 h / 110 - 115 °C

3: ethanolamine / 16 h / 20 °C

With ethanolamine; triethylamine; In dichloromethane; N,N-dimethyl-formamide;