Taurohyodeoxycholic acid sodium salt hydrate

Base Information

• Chemical Name: Taurohyodeoxycholic acid sodium salt hydrate
• CAS No.: 38411-85-7
• Molecular Formula: C26H44NO6SNaxH2O
• Molecular Weight: 523.7

Synonyms:Taurohyodeoxycholic acid sodium salt hydrate;Taurohyodeoxycholic acid hydrate sodium salt;Sodium taurohyodeoxycholate hydrate,Taurohyodeoxycholic acid sodium salt hydrate

Chemical Property of Taurohyodeoxycholic acid sodium salt hydrate

Chemical Property:

• PSA: 132.31000
• LogP: 4.86900

Purity/Quality:

98%min ^*data from raw suppliers

Sodium taurohyodeoxycholate hydrate anionic ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Description: Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid . THDCA decreases the size and weight of human gallstones in vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats. Co-administration of THDCA with taurochenodeoxycholic acid (TCDCA; ) prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats. THDCA also reduces myeloperoxidase activity, expression of TNF-α and IL-6, and colonic damage in a mouse model of TNBS-induced ulcerative colitis.
• Uses: Sodium taurohyodeoxycholate hydrate has been used in a study to assess dose-response data for cytotoxicity, regenerative cell proliferation and secondary oxidative DNA damage in rat livers treated with furan. It has also been used in a study to investigate the use of an immobilized artificial membrane HPLC column to predict bile salt-membrane interactions.

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