Methyl 1-acetyl-1H-indole-6-carboxylate

Base Information

Chemical Name:Methyl 1-acetyl-1H-indole-6-carboxylate
CAS No.:126759-62-4
Molecular Formula:C12H11NO3
Molecular Weight:217.224
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80585300
Nikkaji Number:J258.263E
Wikidata:Q82477213
Mol file:126759-62-4.mol

Synonyms:Methyl 1-acetyl-1H-indole-6-carboxylate;126759-62-4;METHYL 1-ACETYLINDOLE-6-CARBOXYLATE;DTXSID80585300;BFA75962;Methyl1-acetyl-1H-indole-6-carboxylate

Suppliers and Price of Methyl 1-acetyl-1H-indole-6-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl1-acetyl-1H-indole-6-carboxylate 95+%
5g
$ 321.00

Chemenu
methyl1-acetyl-1H-indole-6-carboxylate 95%
5g
$ 303.00

Alichem
Methyl1-acetyl-1H-indole-6-carboxylate
5g
$ 400.00

Total 5 raw suppliers

Chemical Property of Methyl 1-acetyl-1H-indole-6-carboxylate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:339.404°C at 760 mmHg
Flash Point:159.066°C
PSA：48.30000
Density:1.214g/cm³
LogP:2.08800
Storage Temp.:2-8°C
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:217.07389321
Heavy Atom Count:16
Complexity:303

Purity/Quality:

99% ^*data from raw suppliers

Methyl1-acetyl-1H-indole-6-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)N1C=CC2=C1C=C(C=C2)C(=O)OC

Technology Process of Methyl 1-acetyl-1H-indole-6-carboxylate

There total 4 articles about Methyl 1-acetyl-1H-indole-6-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: C₁₄H₁₅NO₅

: 126759-62-4
methyl 1-acetyl-1H-indole-6-carboxylate

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃; for 6h;
DOI:10.1021/acs.orglett.6b03244

Reference yield: 57.0%

: 126759-56-6
2-ethenyl-5-methoxycarbonylacetanilide

: 126759-62-4
methyl 1-acetyl-1H-indole-6-carboxylate

Guidance literature:: With oxygen; copper(l) chloride; palladium dichloride; In 1,2-dimethoxyethane; under 760 Torr;

Reference yield:

: 126759-49-7
3-Acetylamino-4-bromo-benzoic acid methyl ester

: 126759-62-4
methyl 1-acetyl-1H-indole-6-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / tri-o-tolylphosphine, triethylamine / palladium(II) acetate / acetonitrile / 24 h / 120 °C / 22800 Torr

2: 57 percent / oxygen / palladium(II) chloride, copper(I) chloride / 1,2-dimethoxy-ethane / 760 Torr

With oxygen; triethylamine; tris-(o-tolyl)phosphine; palladium diacetate; copper(l) chloride; palladium dichloride; In 1,2-dimethoxyethane; acetonitrile;