2-Furoylacetonitrile

Base Information

Chemical Name:2-Furoylacetonitrile
CAS No.:31909-58-7
Molecular Formula:C7H5NO2
Molecular Weight:135.122
Hs Code.:29321900
European Community (EC) Number:625-817-5
DSSTox Substance ID:DTXSID90185759
Nikkaji Number:J1.275.201F
Wikidata:Q69759013
Mol file:31909-58-7.mol

Synonyms:2-Furoylacetonitrile;31909-58-7;3-(furan-2-yl)-3-oxopropanenitrile;3-(2-furyl)-3-oxopropanenitrile;beta-oxo-2-Furanpropanenitrile;2-(2-furanoyl)acetonitrile;2-cyanoacetylfuran;3-(Fur-2-yl)-3-oxopropanenitrile;2-furanoylacetonitrile;2-furoyl acetonitrile;2-Furoylacetonitrile, 97%;SCHEMBL135923;beta-oxo-2-furanepropanenitrile;RZNSHBXVTAHWPP-UHFFFAOYSA-;DTXSID90185759;3-furan-2-yl-3-oxopropanenitrile;HMS1750E20;3-Furan-2-yl-3-oxo-propionitrile;STR07414;MFCD00052210;AKOS000206984;AM10033;CS-W013361;SB61243;A5750;FT-0604166;EN300-14058;W11912;J-018568;Z96092816;F2135-1131;InChI=1/C7H5NO2/c8-4-3-6(9)7-2-1-5-10-7/h1-2,5H,3H2

Suppliers and Price of 2-Furoylacetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
β-oxo-2-Furanpropanenitrile
10g
$ 1055.00

TRC
β-oxo-2-Furanpropanenitrile
1g
$ 130.00

SynQuest Laboratories
3-(Fur-2-yl)-3-oxopropanenitrile
1 g
$ 32.00

SynQuest Laboratories
3-(Fur-2-yl)-3-oxopropanenitrile
5 g
$ 96.00

Sigma-Aldrich
2-Furoylacetonitrile 97%
5g
$ 97.80

Oakwood
2-Furoylacetonitrile 98%
5g
$ 45.00

Matrix Scientific
3-(Fur-2-yl)-3-oxopropanenitrile >95%
1g
$ 54.00

Heterocyclics
3-(Furan-2-yl)-3-oxopropanenitrile 97%
5g
$ 51.00

Heterocyclics
3-(Furan-2-yl)-3-oxopropanenitrile 97%
25g
$ 210.00

Crysdot
3-(Furan-2-yl)-3-oxopropanenitrile 95+%
100g
$ 640.00

Total 22 raw suppliers

Chemical Property of 2-Furoylacetonitrile

Chemical Property:

Appearance/Colour:beige to light brown powder
Vapor Pressure:0.00137mmHg at 25°C
Melting Point:81-85 °C(lit.)
Refractive Index:1.494
Boiling Point:297.2 °C at 760 mmHg
PKA:7.12±0.10(Predicted)
Flash Point:133.6 °C
PSA：54.00000
Density:1.188 g/cm³
LogP:1.37598
XLogP3:0.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:135.032028402
Heavy Atom Count:10
Complexity:179

Purity/Quality:

99%, ^*data from raw suppliers

β-oxo-2-Furanpropanenitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi,Xn
Hazard Codes:Xn,Xi
Statements: 20/21/22-36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=COC(=C1)C(=O)CC#N
Uses 2-Furoylacetonitrile is used in the synthesis of compounds that display anti-Trypanosoma cruzi activity. This is primarily for combating Chagas disease. β-oxo-2-Furanpropanenitrile is used in the synthesis of compounds that display anti-Trypanosoma cruzi activity. This is primarily for combating Chagas disease.

Technology Process of 2-Furoylacetonitrile

There total 23 articles about 2-Furoylacetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 326-90-9
4,4,4-trifluoro-1-(2-furanyl)-1,3-butanedione

: C₁₂H₂₀N₃S⁽¹⁺⁾*Br^(1-)

: 31909-58-7
2-furoylacetonitrile

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 8h;

Reference yield: 95.0%

: 144223-33-6
2-furoyl-1H-1,2,3-benzotriazole

: 75-05-8,26809-02-9
acetonitrile

: 31909-58-7
2-furoylacetonitrile

Guidance literature:: acetonitrile; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

2-furoyl-1H-1,2,3-benzotriazole; In tetrahydrofuran; hexane; at -78 ℃; for 2h;
DOI:10.1021/jo026796x

Reference yield: 90.0%

: 326-90-9
4,4,4-trifluoro-1-(2-furanyl)-1,3-butanedione

: 19158-51-1
P-toluenesulfonyl cyanide

: 31909-58-7
2-furoylacetonitrile

Guidance literature:: 4,4,4-trifluoro-1-(2-furanyl)-1,3-butanedione; P-toluenesulfonyl cyanide; With potassium carbonate; In tetrahydrofuran; water; at 20 ℃; for 0.5h;

With hydrogenchloride; In tetrahydrofuran; water; at 0 ℃; pH=Ca. 2;
DOI:10.1039/c3ra41376d