20-Hmaop

Base Information

Chemical Name:20-Hmaop
CAS No.:96000-11-2
Molecular Formula:C₂₁H₃₅NO₃
Molecular Weight:349.514
Hs Code.:
DSSTox Substance ID:DTXSID60914694
Wikidata:Q76009858
Mol file:96000-11-2.mol

Synonyms:20-(hydroxymethyl)-4-methyl-4-aza-2-oxapregnan-3-one;20-HMAOP;20-hydroxymethyl-4-methyl-4-aza-2-oxa-5 alpha-pregnan-3-one

Suppliers and Price of 20-Hmaop

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 20-Hmaop

Chemical Property:

Vapor Pressure:3.35E-12mmHg at 25°C
Boiling Point:502.5°C at 760 mmHg
Flash Point:257.7°C
PSA：49.77000
Density:1.084g/cm³
LogP:3.86210
XLogP3:4.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:349.26169398
Heavy Atom Count:25
Complexity:551

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CO)C1CCC2C1(CCC3C2CCC4C3(COC(=O)N4C)C)C
Isomeric SMILES:C[C@H](CO)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(COC(=O)N4C)C)C

Technology Process of 20-Hmaop

There total 2 articles about 20-Hmaop which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.4%

: 96000-17-8
20-(hydroxymethyl)-4-methyl-4-aza-A-dinor-1,3-seco-5α-pregnan-1-ol

: 530-62-1
1,1'-carbonyldiimidazole

: 96000-11-2
20-(hydroxymethyl)-4-methyl-4-aza-2-oxa-5α-pregnan-3-one

Guidance literature:: In tetrahydrofuran; Ambient temperature;
DOI:10.1021/jm00383a026

Reference yield:

: 96000-16-7
2-Hydroxy-N-[(3R,3aS,5aS,6R,7R,9aS,9bS)-6-hydroxymethyl-3-(2-hydroxy-1-methyl-ethyl)-3a,6-dimethyl-dodecahydro-cyclopenta[a]naphthalen-7-yl]-N-methyl-acetamide

: 96000-11-2
20-(hydroxymethyl)-4-methyl-4-aza-2-oxa-5α-pregnan-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / methanol; H₂O / 4 h / Heating

2: 47.4 percent / tetrahydrofuran / Ambient temperature

With potassium hydroxide; In tetrahydrofuran; methanol; water;
DOI:10.1021/jm00383a026