rudmollin

Base Information

Chemical Name:rudmollin
CAS No.:76467-15-7
Molecular Formula:C₁₅H₂₂O₄
Molecular Weight:266.337
Hs Code.:
Mol file:76467-15-7.mol

Synonyms:Rudmollin;

Suppliers and Price of rudmollin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of rudmollin

Chemical Property:

Vapor Pressure:1.27E-10mmHg at 25°C
Boiling Point:465.5°Cat760mmHg
Flash Point:174.5°C
PSA：66.76000
Density:1.23g/cm³
LogP:1.26370

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of rudmollin

There total 21 articles about rudmollin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 928-91-6
(Z)-4-hexenol

: 76467-15-7,105560-90-5
(+/-)-rudmollin

Guidance literature:: Multi-step reaction with 20 steps

1: 54 percent / PCC / CH₂Cl₂ / 2 h / 0 - 25 °C

2: 1.) Mg / 2.) THF, 0deg C, 1.5 h

3: 97 percent / DMAP, Et₃N / dimethylformamide / 10 h / 25 °C

4: pentane / 25 °C / Irradiation

5: 71 percent / Hg(OAc)2 / tetrahydrofuran; H₂O / 0.25 h / 25 °C

6: 94 percent / NaBH₄ / methanol / 0.25 h / 25 °C

7: 93 percent / MnO₂ / CH₂Cl₂ / 24 h / 25 °C

8: 99 percent / H₂ / 5percent Pd/C / diethyl ether / 11 h / 25 °C / 760 Torr

9: 95 percent / DMAP, Et₃N / dimethylformamide / 36 h / 46 - 50 °C

11: 72 percent / NaBH₄, CeCl₃ / methanol / 3 h / -78 °C

12: 1.) O₃, 2.) NaBH₄ / 1. MeOH, CH₂Cl₂, -78 gradC; 2. -78 gradC to 25 gradC

13: 97 percent / imidazole / dimethylformamide / 5 h / 25 °C

14: 1.) MsCl, pyridine, 2.) LAH / 1. 25 gradC, 17 h.; 2. DME, 0 gradC to 25 gradC, 17 h.

15: 96 percent / KH / tetrahydrofuran / 1.5 h / 25 °C

16: 1.) HF/H₂O, 2.) Jones reagent / 1. CH₃CN, THF, 25 gradC, 3 h; 2. CH₃COCH₃, 0 gradC to 25 gradC, 15 min.

17: 1. I₂, 2,4,6-collidine, CH₃CN, 25 gradC, 35 min; 2. Bu₃SnH, AIBN, PhH, 80 gradC, 6 h.

18: 92 percent / NaBH₄ / methanol / -78 - 25 °C

19: 82 percent / H₂ / 10percent Pd/C, 70percent HClO₄ / methanol / 25 °C / 2068.6 Torr

20: 2.) DIBAL / 1. 90 gradC, 50 h; 2. THF, 0 gradC, 1 h.

With pyridine; 1H-imidazole; dmap; manganese(IV) oxide; sodium tetrahydroborate; lithium aluminium tetrahydride; jones reagent; cerium(III) chloride; hydrogen fluoride; mercury(II) diacetate; water; hydrogen; potassium hydride; diisobutylaluminium hydride; ozone; magnesium; methanesulfonyl chloride; triethylamine; pyridinium chlorochromate; palladium on activated charcoal; perchloric acid; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; pentane;
DOI:10.1016/S0040-4039(00)84394-4

Reference yield:

4-hexyn-1-ol: 928-93-8
4-hexyn-1-ol

: 76467-15-7,105560-90-5
(+/-)-rudmollin

Guidance literature:: Multi-step reaction with 21 steps

1: H₂ / Pd/CaCO₃, (Lindlar),quinoline / pentane / 25 °C / 517.1 - 2068.6 Torr

2: 54 percent / PCC / CH₂Cl₂ / 2 h / 0 - 25 °C

3: 1.) Mg / 2.) THF, 0deg C, 1.5 h

4: 97 percent / DMAP, Et₃N / dimethylformamide / 10 h / 25 °C

5: pentane / 25 °C / Irradiation

6: 71 percent / Hg(OAc)2 / tetrahydrofuran; H₂O / 0.25 h / 25 °C

7: 94 percent / NaBH₄ / methanol / 0.25 h / 25 °C

8: 93 percent / MnO₂ / CH₂Cl₂ / 24 h / 25 °C

9: 99 percent / H₂ / 5percent Pd/C / diethyl ether / 11 h / 25 °C / 760 Torr

10: 95 percent / DMAP, Et₃N / dimethylformamide / 36 h / 46 - 50 °C

12: 72 percent / NaBH₄, CeCl₃ / methanol / 3 h / -78 °C

13: 1.) O₃, 2.) NaBH₄ / 1. MeOH, CH₂Cl₂, -78 gradC; 2. -78 gradC to 25 gradC

14: 97 percent / imidazole / dimethylformamide / 5 h / 25 °C

15: 1.) MsCl, pyridine, 2.) LAH / 1. 25 gradC, 17 h.; 2. DME, 0 gradC to 25 gradC, 17 h.

16: 96 percent / KH / tetrahydrofuran / 1.5 h / 25 °C

17: 1.) HF/H₂O, 2.) Jones reagent / 1. CH₃CN, THF, 25 gradC, 3 h; 2. CH₃COCH₃, 0 gradC to 25 gradC, 15 min.

18: 1. I₂, 2,4,6-collidine, CH₃CN, 25 gradC, 35 min; 2. Bu₃SnH, AIBN, PhH, 80 gradC, 6 h.

19: 92 percent / NaBH₄ / methanol / -78 - 25 °C

20: 82 percent / H₂ / 10percent Pd/C, 70percent HClO₄ / methanol / 25 °C / 2068.6 Torr

21: 2.) DIBAL / 1. 90 gradC, 50 h; 2. THF, 0 gradC, 1 h.

With pyridine; 1H-imidazole; dmap; manganese(IV) oxide; sodium tetrahydroborate; lithium aluminium tetrahydride; jones reagent; cerium(III) chloride; hydrogen fluoride; mercury(II) diacetate; water; hydrogen; potassium hydride; diisobutylaluminium hydride; ozone; magnesium; methanesulfonyl chloride; triethylamine; pyridinium chlorochromate; quinoline; palladium on activated charcoal; Lindlar's catalyst; perchloric acid; calcium carbonate; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; pentane;
DOI:10.1016/S0040-4039(00)84394-4

Reference yield:

: 4634-89-3
cis-hex-4-enal

: 76467-15-7,105560-90-5
(+/-)-rudmollin

Guidance literature:: Multi-step reaction with 19 steps

1: 1.) Mg / 2.) THF, 0deg C, 1.5 h

2: 97 percent / DMAP, Et₃N / dimethylformamide / 10 h / 25 °C

3: pentane / 25 °C / Irradiation

4: 71 percent / Hg(OAc)2 / tetrahydrofuran; H₂O / 0.25 h / 25 °C

5: 94 percent / NaBH₄ / methanol / 0.25 h / 25 °C

6: 93 percent / MnO₂ / CH₂Cl₂ / 24 h / 25 °C

7: 99 percent / H₂ / 5percent Pd/C / diethyl ether / 11 h / 25 °C / 760 Torr

8: 95 percent / DMAP, Et₃N / dimethylformamide / 36 h / 46 - 50 °C

10: 72 percent / NaBH₄, CeCl₃ / methanol / 3 h / -78 °C

11: 1.) O₃, 2.) NaBH₄ / 1. MeOH, CH₂Cl₂, -78 gradC; 2. -78 gradC to 25 gradC

12: 97 percent / imidazole / dimethylformamide / 5 h / 25 °C

13: 1.) MsCl, pyridine, 2.) LAH / 1. 25 gradC, 17 h.; 2. DME, 0 gradC to 25 gradC, 17 h.

14: 96 percent / KH / tetrahydrofuran / 1.5 h / 25 °C

15: 1.) HF/H₂O, 2.) Jones reagent / 1. CH₃CN, THF, 25 gradC, 3 h; 2. CH₃COCH₃, 0 gradC to 25 gradC, 15 min.

16: 1. I₂, 2,4,6-collidine, CH₃CN, 25 gradC, 35 min; 2. Bu₃SnH, AIBN, PhH, 80 gradC, 6 h.

17: 92 percent / NaBH₄ / methanol / -78 - 25 °C

18: 82 percent / H₂ / 10percent Pd/C, 70percent HClO₄ / methanol / 25 °C / 2068.6 Torr

19: 2.) DIBAL / 1. 90 gradC, 50 h; 2. THF, 0 gradC, 1 h.

With pyridine; 1H-imidazole; dmap; manganese(IV) oxide; sodium tetrahydroborate; lithium aluminium tetrahydride; jones reagent; cerium(III) chloride; hydrogen fluoride; mercury(II) diacetate; water; hydrogen; potassium hydride; diisobutylaluminium hydride; ozone; magnesium; methanesulfonyl chloride; triethylamine; palladium on activated charcoal; perchloric acid; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; pentane;
DOI:10.1016/S0040-4039(00)84394-4