Chemical Property of Lysophosphatidylethanolamines, egg
Chemical Property:
- Purity/Quality:
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>99% *data from raw suppliers
Lysophosphatidylethanolamines (egg) ≥98% *data from reagent suppliers
Safty Information:
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Useful:
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Description
Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). It increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 and PD 98059 and the EGFR inhibitor AG-1478 . LPE also increases neurite outgrowth and expression of neurofilament M in PC12 cells. LPE inhibits the activity of phospholipase D (PLD) partially purified from cabbage. Lysophosphatidylethanolamines (egg) is a mixture of lysophosphatidylethanolamines isolated from chicken egg with fatty acyl groups of variable lengths at the sn-1 position and a hydroxy group at the sn-2 position.
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Uses
Lysophosphatidyletha?nolamines, Egg is a natural Glycerophospholipid. Glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states.