5-CHLOROSACCHARIN

Base Information

• Chemical Name: 5-CHLOROSACCHARIN
• CAS No.: 29083-16-7
• Molecular Formula: C7H4 Cl N O3 S
• Molecular Weight: 217.63
• Hs Code.: 2934100090
• Mol file: 29083-16-7.mol

Synonyms:1,2-Benzisothiazolin-3-one,5-chloro-, 1,1-dioxide (7CI,8CI); 5-Chloro-1,2-benzisothiazol-3(2H)-one 1,1-dioxide;5-Chloro-1,2-benzisothiazol-3-one 1,1-dioxide; 5-Chlorosaccharin

Chemical Property of 5-CHLOROSACCHARIN

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 75.11000
• Density: 1.679g/cm³
• LogP: 1.86330

Purity/Quality:

99%+ ^*data from raw suppliers

5-Chlorosaccharin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-CHLOROSACCHARIN

There total 12 articles about 5-CHLOROSACCHARIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-(tert-butyl)-5-chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide → 5-chloro-1,2-benzoisothiazolin-3-one 1,1-dioxide (29083-16-7)

Guidance literature:

With trifluoroacetic acid; for 70h; Reflux;

DOI:10.3109/14756366.2015.1057722

Reference yield: 78.0%

→ 5-chloro-1,2-benzoisothiazolin-3-one 1,1-dioxide (29083-16-7)

Guidance literature:

With chromium(VI) oxide; periodic acid; In acetonitrile; for 1h; Reflux;

Reference yield: 76.0%

5-chloro-2-methyl-benzenesulfonamide (85019-87-0) → 5-chloro-1,2-benzoisothiazolin-3-one 1,1-dioxide (29083-16-7)

Guidance literature:

With chromium(VI) oxide; periodic acid; In acetonitrile; for 1h; Heating;

DOI:10.1016/j.tet.2006.05.038

upstream raw materials:

2-tert-butylsulfamoyl-5-chloro-benzoic acid

5-chloro-3,3-difluoro-3H-benzo[c][1,2]oxathiole 1,1-dioxide

5-chloro-2-methyl-benzenesulfonamide

4-chlorobenzenesulfonyl chloride