Mithramycin A

Base Information

• Chemical Name: Mithramycin A
• CAS No.: 97666-60-9
• Molecular Formula: C₅₂H₇₆O₂₄
• Molecular Weight: 1085.16
• Mol file: 97666-60-9.mol

Synonyms:Mithramycin(8CI);A 2371;Antibiotic LA 7017;Aureolic acid;Mithracin;Mitramycin;NSC 24559;PA 144;Plicamycin;Plicatomycin;[1S(2S,3S)]-5-Deoxy-1-C-[7-[[2,6-dideoxy-3-O-(2,6-dideoxy-b-D-arabino-hexopyranosyl)-b-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-b-D-ribo-hexopyranosyl-(1?;3)-O-2,6-dideoxy-b-D-arabino-hexopyranosyl-(1?;3)-2,6-dideoxy-b-D-lyxo-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose;

Chemical Property of Mithramycin A

Chemical Property:

• Boiling Point: 1169.8°Cat760mmHg
• Flash Point: 327.4°C
• Density: 1.48g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Mithramycin A

There total 3 articles about Mithramycin A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ mithramycin (18378-89-7,97666-60-9)

Guidance literature:

Reference yield:

premithramycin B → mithramycin A (97666-60-9)

Guidance literature:

Multi-step reaction with 3 steps

1: Baeyer?Villiger monooxygenase MtmOIV / Enzymatic reaction

2: water

3: ketoreductase MtmW / Enzymatic reaction

With Baeyer?Villiger monooxygenase MtmOIV; ketoreductase MtmW; water;

DOI:10.1021/cb400399b

Reference yield:

mithramycin DK → mithramycin A (97666-60-9)

Guidance literature:

With ketoreductase MtmW; Enzymatic reaction;

DOI:10.1021/cb400399b

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