18,19-Didehydro-10-methoxy-16-[(S)-2,3,4,9-tetrahydro-6-methoxy-1H-pyrido[3,4-b]indol-1-yl]-17-norcorynan

Base Information

• Chemical Name: 18,19-Didehydro-10-methoxy-16-[(S)-2,3,4,9-tetrahydro-6-methoxy-1H-pyrido[3,4-b]indol-1-yl]-17-norcorynan
• CAS No.: 10438-17-2
• Molecular Formula: C₃₁H₃₆N₄O₂
• Molecular Weight: 496.652
• Mol file: 10438-17-2.mol

Synonyms:17-Norcorynan,18,19-didehydro-10-methoxy-16-(2,3,4,9-tetrahydro-6-methoxy-1H-pyrido[3,4-b]indol-1-yl)-,[16(S)]-; Indolo[2,3-a]quinolizine,3-ethenyl-1,2,3,4,6,7,12,12b-octahydro-9-methoxy-2-[[(1S)-2,3,4,9-tetrahydro-6-methoxy-1H-pyrido[3,4-b]indol-1-yl]methyl]-,(2R,3R,12bS)- (9CI); Isocinchophyllamine (8CI); 1H-Pyrido[3,4-b]indole,17-norcorynan deriv.; 3a,17a-Cinchophylline

Chemical Property of 18,19-Didehydro-10-methoxy-16-[(S)-2,3,4,9-tetrahydro-6-methoxy-1H-pyrido[3,4-b]indol-1-yl]-17-norcorynan

Chemical Property:

• Melting Point: 152°C (dec.).
• PSA: 65.31000
• LogP: 5.93150

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: ledgeriana. It is slightly dextrorotatory with a specific rotation of [α]20D + 7° (c 0.5, CHCI3). The crystal structure has recently been determined.

Technology Process of 18,19-Didehydro-10-methoxy-16-[(S)-2,3,4,9-tetrahydro-6-methoxy-1H-pyrido[3,4-b]indol-1-yl]-17-norcorynan

There total 1 articles about 18,19-Didehydro-10-methoxy-16-[(S)-2,3,4,9-tetrahydro-6-methoxy-1H-pyrido[3,4-b]indol-1-yl]-17-norcorynan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dehydro-17,4' 3α cinchophylline → 3α, 17β cinchophylline (1355-62-0) + isocinchophyllamine (10438-17-2)

Guidance literature:

With potassium borohydride; In methanol; for 5h; Title compound not separated from byproducts; Ambient temperature;

DOI:10.1016/S0031-9422(00)91046-X

Refernces