28-Oxo-D:A-friedooleanan-3-one

Base Information

• Chemical Name: 28-Oxo-D:A-friedooleanan-3-one
• CAS No.: 14440-40-5
• Molecular Formula: C₃₀H₄₈O₂
• Molecular Weight: 440.71
• Mol file: 14440-40-5.mol

Synonyms:D:A-Friedooleanan-28-al,3-oxo- (8CI); 3-Oxo-D:A-friedooleanan-28-al; Canophyllal

Chemical Property of 28-Oxo-D:A-friedooleanan-3-one

Chemical Property:

• Melting Point: 263-265 °C
• Boiling Point: 505.7±23.0 °C(Predicted)
• PSA: 34.14000
• Density: 1.025±0.06 g/cm3(Predicted)
• LogP: 7.63600

Purity/Quality:

Analysis control,98.5% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 28-Oxo-D:A-friedooleanan-3-one

There total 3 articles about 28-Oxo-D:A-friedooleanan-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-oxo-28-hydroxyfriedelane (14440-41-6) → canophyllal (14440-40-5)

Guidance literature:

With dipyridine chromium trioxide;

DOI:10.1016/S0040-4020(01)82592-8

Reference yield:

3,28-dioxo-D:A-friedooleanan-25-yl acetate (82784-30-3) → canophyllal (14440-40-5)

Guidance literature:

With pyridine; chromium(VI) oxide; lithium 2-aminoethylamide; Yield given. Multistep reaction; 1.) reflux, 30 min, 2.) 27 degC;

DOI:10.1016/S0040-4039(00)87252-4

Reference yield:

25-hydroxy-3-oxo-D:A-friedooleanan-28-al (82784-28-9) → canophyllal (14440-40-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 35 mg / pyridine / 18 h / 27 °C

2: 1.) ethylenediamine, lithium, 2.) pyridine, CrO₃ / 1.) reflux, 2.) 27 deg C, 12 h

With pyridine; chromium(VI) oxide; lithium; ethylenediamine;

DOI:10.1071/CH9831067

upstream raw materials:

3-oxo-28-hydroxyfriedelane

3,28-dioxo-D:A-friedooleanan-25-yl acetate

25-hydroxy-3-oxo-D:A-friedooleanan-28-al

Downstream raw materials:

3-oxo-28-hydroxyfriedelane

D:A-friedo-oleanane

Refernces

• 1、 Weeratunga, Gamini,Kumar, Vijaya,Sultanbawa, M. Uvais S.. "D:A-Friedooleananes from Elaeodendron glaucum". . p. 1067 - 1072. Retrieved 2007/10/02.