1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-3,4-dihydroisoquinoline Hydrochloride

Base Information

Chemical Name:1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-3,4-dihydroisoquinoline Hydrochloride
CAS No.:911-60-4
Molecular Formula:C₂₄H₃₁NO₄*ClH
Molecular Weight:433.975
Hs Code.:
DSSTox Substance ID:DTXSID00919961

Synonyms:1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-3,4-dihydroisoquinoline Hydrochloride;SCHEMBL7521568;DTXSID00919961;AKOS030557595;EN300-05114;SR-01000524010;SR-01000524010-1;Z56896159;1-(3,4-diethoxybenzyl)-6,7-diethoxy-3,4-dihydroisoquinoline hydrochloride;1-[(3,4-Diethoxyphenyl)methyl]-6,7-diethoxy-3,4-dihydroisoquinoline--hydrogen chloride (1/1)

Suppliers and Price of 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-3,4-dihydroisoquinoline Hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-3,4-dihydroisoquinoline Hydrochloride

Chemical Property:

Vapor Pressure:1.14E-10mmHg at 25°C
Boiling Point:527°Cat760mmHg
Flash Point:217.7°C
Density:g/cm³
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:433.2019862
Heavy Atom Count:30
Complexity:511

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=C(C=C(C=C1)CC2=NCCC3=CC(=C(C=C32)OCC)OCC)OCC.Cl

Technology Process of 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-3,4-dihydroisoquinoline Hydrochloride

There total 9 articles about 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-3,4-dihydroisoquinoline Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17345-77-6
1-bromo-3,4-dihydroxybenzene

: 911-60-4
1-(3',4'-diethoxybenzyl)-6,7-diethoxy-3,4-dihydroisoquinoline hydrochloride

Guidance literature:: Multi-step reaction with 6 steps

1: potassium hydroxide / acetonitrile / 70 - 80 °C

2: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 90 - 100 °C

3: potassium dihydrogenphosphate / 1,4-dioxane; water / 90 - 100 °C

4: sodium hydroxide / 1,4-dioxane / 50 - 60 °C

5: 100 - 120 °C / Inert atmosphere

6: trichlorophosphate / toluene / 40 - 70 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium dihydrogenphosphate; potassium acetate; potassium hydroxide; sodium hydroxide; trichlorophosphate; In 1,4-dioxane; water; toluene; acetonitrile; 2: |Suzuki-Miyaura Coupling / 3: |Suzuki-Miyaura Coupling;

Reference yield:

: 53207-08-2
4-bromo-1,2-diethoxybenzene

: 911-60-4
1-(3',4'-diethoxybenzyl)-6,7-diethoxy-3,4-dihydroisoquinoline hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 90 - 100 °C

2: potassium dihydrogenphosphate / 1,4-dioxane; water / 90 - 100 °C

3: sodium hydroxide / 1,4-dioxane / 50 - 60 °C

4: 100 - 120 °C / Inert atmosphere

5: trichlorophosphate / toluene / 40 - 70 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium dihydrogenphosphate; potassium acetate; sodium hydroxide; trichlorophosphate; In 1,4-dioxane; water; toluene; 1: |Suzuki-Miyaura Coupling / 2: |Suzuki-Miyaura Coupling;

Reference yield:

: 1005009-95-9
2-(3,4-diethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 911-60-4
1-(3',4'-diethoxybenzyl)-6,7-diethoxy-3,4-dihydroisoquinoline hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: potassium dihydrogenphosphate / 1,4-dioxane; water / 90 - 100 °C

2: sodium hydroxide / 1,4-dioxane / 50 - 60 °C

3: 100 - 120 °C / Inert atmosphere

4: trichlorophosphate / toluene / 40 - 70 °C

With potassium dihydrogenphosphate; sodium hydroxide; trichlorophosphate; In 1,4-dioxane; water; toluene; 1: |Suzuki-Miyaura Coupling;