2-Chloro-4-nitrobenzanilide

Base Information

• Chemical Name: 2-Chloro-4-nitrobenzanilide
• CAS No.: 71501-31-0
• Molecular Formula: C13H9 Cl N2 O3
• Molecular Weight: 276.679
• European Community (EC) Number: 275-560-4
• NSC Number: 158651
• UNII: Q5NX52RUW3
• DSSTox Substance ID: DTXSID00221733
• Nikkaji Number: J289.184K
• Wikidata: Q83099673
• Mol file: 71501-31-0.mol

Synonyms:2-Chloro-4-nitrobenzanilide;71501-31-0;2-chloro-4-nitro-n-phenylbenzamide;Q5NX52RUW3;EINECS 275-560-4;NSC-158651;2-CHLORO-4-NITRO BENZANILIDE;NSC158651;UNII-Q5NX52RUW3;SCHEMBL8310013;DTXSID00221733;MFCD00017012;AKOS001306029;NSC 158651;FT-0745292;BENZAMIDE, 2-CHLORO-4-NITRO-N-PHENYL-;Z27782736

Chemical Property of 2-Chloro-4-nitrobenzanilide

Chemical Property:

• Vapor Pressure: 1.26E-05mmHg at 25°C
• Boiling Point: 368.6°C at 760 mmHg
• Flash Point: 176.7°C
• PSA: 74.92000
• Density: 1.44g/cm³
• LogP: 4.09670
• Solubility.: Chloroform, Methanol
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 276.0301698
• Heavy Atom Count: 19
• Complexity: 339

Purity/Quality:

99% ^*data from raw suppliers

2-CHLORO-4'-NITROBENZANILIDE AldrichCPR ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NC(=O)C2=C(C=C(C=C2)[N+](=O)[O-])Cl

Technology Process of 2-Chloro-4-nitrobenzanilide

There total 3 articles about 2-Chloro-4-nitrobenzanilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

4-amino-2-chlorobenzanilide + 2-chloro-4-nitrobenzoyl chloride (7073-36-1) → N-phenyl benzoyl amide (93-98-1,5705-51-1) + 2-chloro-4-nitro-benzoic acid anilide (71501-31-0)

Guidance literature:

With aniline;

Reference yield:

2-chloro-4-nitrobenzoic acid (99-60-5) → 2-chloro-4-nitro-benzoic acid anilide (71501-31-0)

Guidance literature:

Multi-step reaction with 2 steps

1: PCl₅

With phosphorus pentachloride;

Reference yield:

2-chloro-4-nitrobenzoyl chloride (7073-36-1) + aniline (62-53-3) → 2-chloro-4-nitro-benzoic acid anilide (71501-31-0)

Guidance literature:

upstream raw materials:

2-chloro-4-nitrobenzoyl chloride

aniline

2-chloro-4-nitrobenzoic acid