2-(Cyclohex-1-en-1-yl)-1,4-dimethoxybenzene

Base Information

• Chemical Name: 2-(Cyclohex-1-en-1-yl)-1,4-dimethoxybenzene
• CAS No.: 1848-14-2
• Molecular Formula: C14H18 O2
• Molecular Weight: 218.2915
• NSC Number: 127374
• DSSTox Substance ID: DTXSID40298984
• Wikidata: Q82041129
• Mol file: 1848-14-2.mol

Synonyms:2-(cyclohex-1-en-1-yl)-1,4-dimethoxybenzene;1848-14-2;2-(cyclohexen-1-yl)-1,4-dimethoxybenzene;NSC127374;2-(1-cyclohexen-1-yl)-1,4-dimethoxybenzene;DTXSID40298984;NSC-127374;AQ-387/42302697

Chemical Property of 2-(Cyclohex-1-en-1-yl)-1,4-dimethoxybenzene

Chemical Property:

• Vapor Pressure: 0.000103mmHg at 25°C
• Boiling Point: 348.2°Cat760mmHg
• Flash Point: 139.9°C
• Density: 1.039g/cm³
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 218.130679813
• Heavy Atom Count: 16
• Complexity: 247

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C=C1)OC)C2=CCCCC2

Technology Process of 2-(Cyclohex-1-en-1-yl)-1,4-dimethoxybenzene

There total 4 articles about 2-(Cyclohex-1-en-1-yl)-1,4-dimethoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

1-bromo-2,5-dimethoxybenzene (25245-34-5) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → 1-(2,5-dimethoxyphenyl)cyclohexene (1848-14-2)

Guidance literature:

With iodine; magnesium; In diethyl ether; Ambient temperature;

Reference yield:

1--cyclohexan-1-ol (1848-15-3) → 1-(2,5-dimethoxyphenyl)cyclohexene (1848-14-2)

Guidance literature:

With oxalic acid; In toluene; Heating;

DOI:10.1039/jr9650001495

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → 1-(2,5-dimethoxyphenyl)cyclohexene (1848-14-2)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) PhLi, (ii) /BRN= 385735/, (heating)

2: oxalic acid / toluene / Heating

With oxalic acid; In toluene;

DOI:10.1039/jr9650001495

upstream raw materials:

1-bromo-2,5-dimethoxybenzene

cyclohexanone

1--cyclohexan-1-ol

1,4-dimethoxybezene

Downstream raw materials:

1-(2,5-dimethoxyphenyl)cyclohexene oxide

(1R,6R)-1-(2,5-Dimethoxy-phenyl)-7-oxa-bicyclo[4.1.0]heptane

2-(p-Dimethoxy-phenyl)-cyclohex-2-en-1-on-oxim

trans-2-amino-1-(2,5-dimethoxyphenyl)cyclohexanol hydrochloride