Furo[3,4-b]quinoxaline-1,3-dione

Base Information

• Chemical Name: Furo[3,4-b]quinoxaline-1,3-dione
• CAS No.: 5660-34-4
• Molecular Formula: C10H4N2O3
• Molecular Weight: 200.153
• European Community (EC) Number: 227-109-8
• NSC Number: 36328
• UNII: 16A8EJ9WKB
• DSSTox Substance ID: DTXSID90205163
• Nikkaji Number: J225.079I
• Wikidata: Q83078652
• Mol file: 5660-34-4.mol

Synonyms:furo[3,4-b]quinoxaline-1,3-dione;5660-34-4;Furo(3,4-b)quinoxaline-1,3-dione;EINECS 227-109-8;16A8EJ9WKB;NSC 36328;NSC-36328;NSC36328;UNII-16A8EJ9WKB;SCHEMBL9357079;C10H4N2O3;DTXSID90205163;2,3-QUINOXALINIC ANHYDRIDE;quinoxaline-2,3-dicarboxylic acid anhydride;2,3-QUINOXALINEDICARBOXYLIC ANHYDRIDE;6,7-DIMETHYLQUINOXALINE-2,3-DICARBOXYLIC ANHYDRIDE

Chemical Property of Furo[3,4-b]quinoxaline-1,3-dione

Chemical Property:

• Vapor Pressure: 1.25E-07mmHg at 25°C
• Boiling Point: 430.9°Cat760mmHg
• Flash Point: 214.4°C
• Density: 1.625g/cm³
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 200.02219199
• Heavy Atom Count: 15
• Complexity: 288

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)N=C3C(=N2)C(=O)OC3=O

Technology Process of Furo[3,4-b]quinoxaline-1,3-dione

There total 7 articles about Furo[3,4-b]quinoxaline-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

Quinoxaline-2,3-dicarboxylic acid (6924-99-8) → quinoxaline-2,3-dicarboxylic acid anhydride (5660-34-4)

Guidance literature:

With acetic anhydride; for 3h; Reflux;

DOI:10.1039/c3cc45469j

Reference yield:

1,2-diamino-benzene (95-54-5) → quinoxaline-2,3-dicarboxylic acid anhydride (5660-34-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride

2: acetic anhydride

With hydrogenchloride; acetic anhydride;

DOI:10.3184/174751911X12983997221326

Reference yield:

→ quinoxaline-2,3-dicarboxylic acid anhydride (5660-34-4)

Guidance literature:

With acetic anhydride; at 130 ℃;

upstream raw materials:

Quinoxaline-2,3-dicarboxylic acid

1,2-diamino-benzene

dimethyl quinoxaline-2,3-dicarboxylate

tert–butyl (2–aminophenyl)carbamate

Downstream raw materials:

phenyl quinoxaline-2-carboxylate

2,3-dihydropyridazino[4,5-b]quinoxaline-1,4-dione

2-hydroxy-pyrrolo[3,4-b]quinoxaline-1,3-dione

3-(3-benzoyl-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylcarbamoyl)-quinoxaline-2-carboxylic acid