Picroside I

Base Information

• Chemical Name: Picroside I
• CAS No.: 27409-30-9
• Deprecated CAS: 31200-45-0
• Molecular Formula: C24H28O11
• Molecular Weight: 492.48
• Hs Code.: 29389090
• European Community (EC) Number: 248-445-1
• DSSTox Substance ID: DTXSID101318188
• Nikkaji Number: J772.077G
• Wikidata: Q105344921
• Metabolomics Workbench ID: 135337
• ChEMBL ID: CHEMBL454577
• Mol file: 27409-30-9.mol

Synonyms:picroside I

Chemical Property of Picroside I

Chemical Property:

• Vapor Pressure: 1.62E-25mmHg at 25°C
• Refractive Index: 1.671
• Boiling Point: 778.6 °C at 760 mmHg
• Flash Point: 267.5 °C
• PSA: 167.67000
• Density: 1.56 g/cm³
• LogP: -1.32600
• Storage Temp.: 2-8°C
• Solubility.: ethanol: soluble1mg/mL, clear, colorless
• XLogP3: -1.1
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 8
• Exact Mass: 492.16316171
• Heavy Atom Count: 35
• Complexity: 826

Purity/Quality:

99%, ^*data from raw suppliers

Picroside I ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=CC(=O)OCC2C(C(C(C(O2)OC3C4C(C=CO3)C(C5C4(O5)CO)O)O)O)O
• Isomeric SMILES: C1=CC=C(C=C1)/C=C/C(=O)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)O[C@H]3[C@H]4[C@@H](C=CO3)[C@@H]([C@H]5[C@@]4(O5)CO)O)O)O)O
• Description: Picroliv is a hepatoprotective mixture of compounds that is isolated from an herb native to the Himalayas. Picroside I is an iridoid glycoside found in picroliv. By itself, picroside I blocks changes in acid phosphatase activity, phospholipid levels, and lipid peroxide production induced by D-galactosamine in rat liver. Picroside I also enhances neurite outgrowth in PC12D cells induced by basic fibroblast growth factor and 7S nerve growth factor when given at 60 μM. At concentrations as low as 5 μM, picroside I enhances the ATPase activity of the efflux transporter P-glycoprotein.
• Uses: Picroside I acts as an oxygen free radical scavenger and thus promotes anti-inflammatory activity and may be used in the treatment of arthritis.