Pyrimido[1,2-a]indol-2(1H)-one, 10a-[2-[4-(dimethylamino)phenyl]ethenyl]-3,4,10,10a-tetrahydro-10,10-dimethyl-

Base Information

Chemical Name:Pyrimido[1,2-a]indol-2(1H)-one, 10a-[2-[4-(dimethylamino)phenyl]ethenyl]-3,4,10,10a-tetrahydro-10,10-dimethyl-
CAS No.:60946-69-2
Molecular Formula:C23H27 N3 O
Molecular Weight:361.487
Hs Code.:
European Community (EC) Number:262-533-7
DSSTox Substance ID:DTXSID30886415
Mol file:60946-69-2.mol

Synonyms:60946-69-2;Pyrimido[1,2-a]indol-2(1H)-one, 10a-[2-[4-(dimethylamino)phenyl]ethenyl]-3,4,10,10a-tetrahydro-10,10-dimethyl-;EINECS 262-533-7;Pyrimido(1,2-a)indol-2(1H)-one, 10a-(2-(4-(dimethylamino)phenyl)ethenyl)-3,4,10,10a-tetrahydro-10,10-dimethyl-;Pyrimido(1,2-a)indole-2-(1H)-one, 3,4,10,10a-tetrahydro-10a-(2-(4-dimethylaminophenyl)ethenyl)-10,10-dimethyl-;10a-(2-(4-(Dimethylamino)phenyl)vinyl)-3,4,10,10a-tetrahydro-10,10-dimethylpyrimido(1,2-a)indol-2(1H)-one;10a-[2-[4-(dimethylamino)phenyl]vinyl]-3,4,10,10a-tetrahydro-10,10-dimethylpyrimido[1,2-a]indol-2(1H)-one;DTXSID30886415;10a-[2-[4-(dimethylamino)phenyl]ethenyl]-10,10-dimethyl-3,4-dihydro-1H-pyrimido[1,2-a]indol-2-one

Suppliers and Price of Pyrimido[1,2-a]indol-2(1H)-one, 10a-[2-[4-(dimethylamino)phenyl]ethenyl]-3,4,10,10a-tetrahydro-10,10-dimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of Pyrimido[1,2-a]indol-2(1H)-one, 10a-[2-[4-(dimethylamino)phenyl]ethenyl]-3,4,10,10a-tetrahydro-10,10-dimethyl-

Chemical Property:

Vapor Pressure:2.5E-13mmHg at 25°C
Boiling Point:577.3°C at 760 mmHg
Flash Point:303°C
PSA：39.07000
Density:1.19g/cm³
LogP:4.12070
XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:361.215412493
Heavy Atom Count:27
Complexity:590

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C2=CC=CC=C2N3C1(NC(=O)CC3)C=CC4=CC=C(C=C4)N(C)C)C

Technology Process of Pyrimido[1,2-a]indol-2(1H)-one, 10a-[2-[4-(dimethylamino)phenyl]ethenyl]-3,4,10,10a-tetrahydro-10,10-dimethyl-

There total 4 articles about Pyrimido[1,2-a]indol-2(1H)-one, 10a-[2-[4-(dimethylamino)phenyl]ethenyl]-3,4,10,10a-tetrahydro-10,10-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 93360-41-9
10,10,10a-trimethyl-1,2,3,4,10,10a-hexahydropyrimido<1,2-a>indol-2-one

: 100-10-7
4-dimethylamino-benzaldehyde

: 60946-69-2
10,10-dimethyl-10a-(4-dimethylaminostyryl)-1,2,3,4,10,10a-hexahydropyrimido<1,2-a>indol-2-one

Guidance literature:: With acetic anhydride; acetic acid; at 100 ℃; for 3h;
DOI:10.1007/BF01175058

Reference yield: 82.0%

: 1-(2-carbamoylethyl)-2,3,3-trimethyl-3H-indolium perchlorate

: 100-10-7
4-dimethylamino-benzaldehyde

: 60946-69-2
10,10-dimethyl-10a-(4-dimethylaminostyryl)-1,2,3,4,10,10a-hexahydropyrimido<1,2-a>indol-2-one

Guidance literature:: With acetic acid; at 100 ℃; for 2h;
DOI:10.1007/BF01175058

Reference yield:

: 1640-39-7
2,3,3-trimethylindoleniune

: 60946-69-2
10,10-dimethyl-10a-(4-dimethylaminostyryl)-1,2,3,4,10,10a-hexahydropyrimido<1,2-a>indol-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / acetic acid / 2 h / 100 °C

2: 91 percent / CH₃COOH,(CH₃CO)2O / 3 h / 100 °C

With acetic anhydride; acetic acid; In acetic acid;
DOI:10.1007/BF01175058