N-[1,2-Bis(4-methoxyphenyl)butyl]-N'-(4-chlorophenyl)thiourea

Base Information

Chemical Name:N-[1,2-Bis(4-methoxyphenyl)butyl]-N'-(4-chlorophenyl)thiourea
CAS No.:76289-20-8
Molecular Formula:C25H27ClN2O2S
Molecular Weight:455.021
Hs Code.:
NSC Number:295450
DSSTox Substance ID:DTXSID90402413
Mol file:76289-20-8.mol

Synonyms:76289-20-8;NSC295450;DTXSID90402413;N-[1,2-Bis(4-methoxyphenyl)butyl]-N'-(4-chlorophenyl)thiourea;NSC-295450

Suppliers and Price of N-[1,2-Bis(4-methoxyphenyl)butyl]-N'-(4-chlorophenyl)thiourea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of N-[1,2-Bis(4-methoxyphenyl)butyl]-N'-(4-chlorophenyl)thiourea

Chemical Property:

Vapor Pressure:4.32E-13mmHg at 25°C
Boiling Point:572°Cat760mmHg
Flash Point:299.7°C
PSA：74.61000
Density:1.224g/cm³
LogP:7.04260
XLogP3:6.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:454.1481770
Heavy Atom Count:31
Complexity:528

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C1=CC=C(C=C1)OC)C(C2=CC=C(C=C2)OC)NC(=S)NC3=CC=C(C=C3)Cl

Technology Process of N-[1,2-Bis(4-methoxyphenyl)butyl]-N'-(4-chlorophenyl)thiourea

There total 3 articles about N-[1,2-Bis(4-methoxyphenyl)butyl]-N'-(4-chlorophenyl)thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 76289-23-1
1,2-bis(p-methoxyphenyl)butylamine

: 2131-55-7
4-Chlorophenyl isothiocyanate

: 76289-20-8
1-[1,2-Bis-(4-methoxy-phenyl)-butyl]-3-(4-chloro-phenyl)-thiourea

Guidance literature:: In ethanol; for 0.5h; Heating;
DOI:10.1002/jps.2600700928

Reference yield:

: 4390-94-7
1,2-bis(4-methoxyphenyl)butanone

: 76289-20-8
1-[1,2-Bis-(4-methoxy-phenyl)-butyl]-3-(4-chloro-phenyl)-thiourea

Guidance literature:: Multi-step reaction with 3 steps

1: NH₂OH*HCl, potassium acetate / ethanol

2: 75 percent / aluminum amalgam / ethanol; H₂O / 48 h

3: 76 percent / ethanol / 0.5 h / Heating

With aluminium amalgam; hydroxylamine hydrochloride; potassium acetate; In ethanol; water;
DOI:10.1002/jps.2600700928

Reference yield:

: 854870-99-8
1,2-bis-(4-methoxy-phenyl)-butan-1-one oxime

: 76289-20-8
1-[1,2-Bis-(4-methoxy-phenyl)-butyl]-3-(4-chloro-phenyl)-thiourea

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / aluminum amalgam / ethanol; H₂O / 48 h

2: 76 percent / ethanol / 0.5 h / Heating

With aluminium amalgam; In ethanol; water;
DOI:10.1002/jps.2600700928