N-[2-(4-carbamothioyl-1,3-thiazol-2-yl)ethyl]benzamide

Base Information

• Chemical Name: N-[2-(4-carbamothioyl-1,3-thiazol-2-yl)ethyl]benzamide
• CAS No.: 30761-34-3
• Molecular Formula: C₁₃H₁₃N₃OS₂
• Molecular Weight: 291.398
• DSSTox Substance ID: DTXSID50401386
• NSC Number: 143139
• Mol file: 30761-34-3.mol

Synonyms:MLS002920581;30761-34-3;NSC143139;DTXSID50401386;NSC-143139;SMR001798169

Chemical Property of N-[2-(4-carbamothioyl-1,3-thiazol-2-yl)ethyl]benzamide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.347g/cm³
• XLogP3: 2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 291.05000439
• Heavy Atom Count: 19
• Complexity: 332

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)NCCC2=NC(=CS2)C(=S)N

Technology Process of N-[2-(4-carbamothioyl-1,3-thiazol-2-yl)ethyl]benzamide

There total 4 articles about N-[2-(4-carbamothioyl-1,3-thiazol-2-yl)ethyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

β-benzamidothiopropionamide (30761-30-9) → 2-(2-benzoylamino-ethyl)-thiazole-4-carbothioic acid amide (30761-34-3)

Guidance literature:

Multi-step reaction with 4 steps

2: NH₃ / methanol

3: POCl₃ / pyridine

4: H₂S

With hydrogen sulfide; ammonia; trichlorophosphate; In pyridine; methanol;

Reference yield:

2-(2-benzoylamino-ethyl)-thiazole-4-carboxylic acid amide (30761-32-1) → 2-(2-benzoylamino-ethyl)-thiazole-4-carbothioic acid amide (30761-34-3)

Guidance literature:

Multi-step reaction with 2 steps

1: POCl₃ / pyridine

2: H₂S

With hydrogen sulfide; trichlorophosphate; In pyridine;

Reference yield:

ethyl 2-<(N-benzoylamino)ethyl>thiazole-4-carboxylate (30761-31-0) → 2-(2-benzoylamino-ethyl)-thiazole-4-carbothioic acid amide (30761-34-3)

Guidance literature:

Multi-step reaction with 3 steps

1: NH₃ / methanol

2: POCl₃ / pyridine

3: H₂S

With hydrogen sulfide; ammonia; trichlorophosphate; In pyridine; methanol;

upstream raw materials:

2-(2-benzoylamino-ethyl)-thiazole-4-carbonitrile

β-benzamidothiopropionamide

2-(2-benzoylamino-ethyl)-thiazole-4-carboxylic acid amide

ethyl 2-<(N-benzoylamino)ethyl>thiazole-4-carboxylate