methyl N-(tert-butoxycarbonyl)tryptophylmethioninate

Base Information

Chemical Name:methyl N-(tert-butoxycarbonyl)tryptophylmethioninate
CAS No.:5934-88-3
Molecular Formula:C22H31 N3 O5 S
Molecular Weight:449.5636
Hs Code.:

Synonyms:L-Methionine,N-[N-[(1,1-dimethylethoxy)carbonyl]-L-tryptophyl]-, methyl ester; Methionine,N-(N-carboxy-L-tryptophyl)-, N-tert-butyl methyl ester (7CI); Methionine,N-(N-carboxy-L-tryptophyl)-, N-tert-butyl methyl ester, L- (8CI); NSC 249280

Suppliers and Price of methyl N-(tert-butoxycarbonyl)tryptophylmethioninate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of methyl N-(tert-butoxycarbonyl)tryptophylmethioninate

Chemical Property:

Vapor Pressure:4.11E-19mmHg at 25°C
Boiling Point:694°C at 760 mmHg
Flash Point:373.5°C
Density:1.217g/cm³

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of methyl N-(tert-butoxycarbonyl)tryptophylmethioninate

There total 5 articles about methyl N-(tert-butoxycarbonyl)tryptophylmethioninate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 2491-18-1
(S)-methyl 2-amino-4-(methylthio)butanoate hydrochloride

: 13139-14-5
Boc-Trp-OH

: 5934-88-3
(S)-methyl 2-((S)-2-((tert-butoxycarbonyl)amino)-3-(1H-indol-3-yl)propanamindo)-4-(methylthio)butanoate

Guidance literature:: With N-ethylmorpholine;; (C₃H₇PO₂)3; In dichloromethane; N,N-dimethyl-formamide; for 25h; Ambient temperature;

Reference yield: 78.0%

: 10332-17-9,874219-77-9
Met-OMe

: 75243-97-9
(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionic acid 3-oxo-2-phenyl-3H-inden-1-yl ester

: 5934-88-3
(S)-methyl 2-((S)-2-((tert-butoxycarbonyl)amino)-3-(1H-indol-3-yl)propanamindo)-4-(methylthio)butanoate

Guidance literature:: With acetic acid; In tetrahydrofuran; for 48h; Ambient temperature;

Reference yield: 70.0%

: 13139-14-5
Boc-Trp-OH

: 93605-54-0
(S)-methyl 2-(1H-imidazole-1-carboxamido)-4-(methylthio)butanoate

: 5934-88-3
(S)-methyl 2-((S)-2-((tert-butoxycarbonyl)amino)-3-(1H-indol-3-yl)propanamindo)-4-(methylthio)butanoate

Guidance literature:: With benzotriazol-1-ol; copper(ll) bromide; In dichloromethane; at 22 ℃; for 20h; Inert atmosphere; Schlenk technique;
DOI:10.1002/anie.201402147