7,7-Dimethoxybicyclo[2.2.1]heptan-2-ol

Base Information

Chemical Name:7,7-Dimethoxybicyclo[2.2.1]heptan-2-ol
CAS No.:10421-72-4
Molecular Formula:C₉H₁₆O₃
Molecular Weight:172.224
Hs Code.:
NSC Number:176909
DSSTox Substance ID:DTXSID00306478
Mol file:10421-72-4.mol

Synonyms:10421-72-4;NSC176909;SCHEMBL5070819;DTXSID00306478;NSC-176909;7,7-dimethoxybicyclo[2.2.1]heptan-2-ol

Suppliers and Price of 7,7-Dimethoxybicyclo[2.2.1]heptan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 7,7-Dimethoxybicyclo[2.2.1]heptan-2-ol

Chemical Property:

Vapor Pressure:0.00884mmHg at 25°C
Boiling Point:235.9°Cat760mmHg
Flash Point:96.5°C
Density:1.12g/cm³
XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:172.109944368
Heavy Atom Count:12
Complexity:177

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1(C2CCC1C(C2)O)OC

Technology Process of 7,7-Dimethoxybicyclo[2.2.1]heptan-2-ol

There total 10 articles about 7,7-Dimethoxybicyclo[2.2.1]heptan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 64145-55-7,112460-49-8,123001-41-2
(+/-)-(1S,2S,4S)-7,7-dimethoxybicyclo[2.2.1]hept-5-en-2-ol

: 10265-41-5,10421-72-4,53448-73-0,53495-35-5,70981-37-2,97858-83-8,123001-30-9,123001-43-4
(1RS,2RS,4SR)-7,7-dimethoxybicyclo[2.2.1]heptan-2-ol

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; for 0.666667h; under 1551.4 Torr; Ambient temperature;
DOI:10.1021/jo00055a037

Reference yield: 88.0%

: 90254-09-4,112460-47-6,133962-63-7
(1RS,2SR,4SR)-7,7-dimethoxy-1,4,5,6-tetrachlorobicyclo<2.2.1>hept-5-en-2-ol

: 10265-41-5,10421-72-4,53448-73-0,53495-35-5,70981-37-2,97858-83-8,123001-30-9,123001-43-4
(1RS,2RS,4SR)-7,7-dimethoxybicyclo[2.2.1]heptan-2-ol

Guidance literature:: With ammonia; sodium; In methanol; for 1h;
DOI:10.1139/v03-086

Reference yield:

: 19448-78-3
1,2,3,4-tetrachloro-7,7-dimethoxybicyclo<2.2.1>hept-2-ene

: 10265-41-5,10421-72-4,53448-73-0,53495-35-5,70981-37-2,97858-83-8,123001-30-9,123001-43-4
7,7-dimethoxybicyclo<2.2.1>heptan-exo-2-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / sodium-liquid ammonia, ethanol / diethyl ether / 0.92 h

2: 1.) mercuric acetate, 2.) sodium borohydride, aq. NaOH / 1.) THF, water, ice-water cooling --> room temperature, 45 min, 2.) 20 min

With sodium hydroxide; sodium tetrahydroborate; ethanol; mercury(II) diacetate; ammonia; sodium; In diethyl ether;
DOI:10.1021/ja00526a038